| Type | Description |
|---|---|
| Definition | synaptojanin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations. | 33349335 |
| 2021-01-23 12:58:00 | TGFbeta receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2alpha-, and INPP4B-mediated phosphoinositide conversions. | 31913757 |
| 2020-09-05 13:53:00 | A novel homozygous SYNJ1 mutation in two siblings with typical Parkinson's disease. | 31751865 |
| 2019-11-02 13:25:00 | SYNJ1 contributes to memory deficits in the aging hippocampus in all forms of Alzheimer's disease. | 29874583 |
| 2019-11-02 10:53:00 | Data indicate that Synj1 plays a crucial role in regulating the homeostasis and functions of early endosomal compartments in different cell types, and highlight defective cellular pathways in PARK20. In addition, they strengthen the link between endosomal trafficking and Parkinson's disease. | 29515184 |
| Type | IDs |
|---|---|
| Synonymous | EIEE53, INPP5G, PARK20 |
| Gene |
UniProtKB-ID:
SYNJ1_HUMAN,
B9EGN3_HUMAN,
Q05CZ1_HUMAN,
J3KQV8_HUMAN,
A0A0D9SGJ6_HUMAN,
C9JFZ1_HUMAN
UniprotKB:
O43426,
B9EGN3,
Q05CZ1,
J3KQV8,
A0A0D9SGJ6,
C9JFZ1
UniParc:
UPI000034ECCC,
UPI0000D4980F,
UPI000066D9B0,
UPI000192C421,
UPI000198C848,
UPI000054E49E,
UPI0000206D91,
UPI0001A47572,
UPI0001A47574
EMBL:
AP000279,
BC136603,
AF009039,
AP000278,
AP000277,
BC098395,
BC019630,
KC877861,
AF009040,
AP000275,
AP000276,
KF510544,
AB020717
Ensembl:
ENSG00000159082
KO:
hsa:8867
|
| Nucleutide sequences |
EMBL-CDS:
AAC51921.1,
AAH98395.1,
AAC51922.1,
BAA74933.2,
AAI36604.1,
AAH19630.1
Ensembl_TRS:
ENST00000674204,
ENST00000674351,
ENST00000357345,
ENST00000674308,
ENST00000433931,
ENST00000630077,
ENST00000382499
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000501504,
ENSP00000349903,
ENSP00000501530,
ENSP00000501426,
ENSP00000409667,
ENSP00000487560,
ENSP00000371939
RefSeq:
XP_016883990.1,
XP_016883984.1,
XP_016883994.1,
XP_016883988.1,
XP_016883985.1,
XP_016883991.1,
XP_016883993.1,
XP_016883987.1,
XP_016883989.1,
NP_982271.3,
XP_016883992.1,
NP_003886.3,
XP_016883986.1,
XP_016883983.1,
NP_001153774.1,
NP_001153778.1
|
| Others |
UniRef100:
UniRef100_O43426,
UniRef100_Q05CZ1,
UniRef100_C9JFZ1,
UniRef100_B9EGN3,
UniRef100_A0A0D9SGJ6
UniRef90:
UniRef90_O43426-5,
UniRef90_B9EGN3,
UniRef90_G1Q6W5,
UniRef90_O43426
UniRef50:
UniRef50_G1QF26,
UniRef50_Q62910,
UniRef50_E9QHF3
UniGene:
Hs.473632
CCDS:
CCDS33540.2,
CCDS54483.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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