| Type | Description |
|---|---|
| Definition | serine/threonine-protein kinase PknG |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 12:15:00 | results show that PknG phosphorylates specific residues in both glutamine synthetase and FhaA in vitro, and suggest that these proteins are phosphorylated by PknG in living mycobacteria. | 30267874 |
| 2018-07-14 10:35:00 | data strongly suggests that pknG regulates growth of mycobacteria in acidic environment and is differentially transcribed in MS and Mtb under these conditions. | 29124568 |
| 2017-11-25 14:08:00 | Sclerotiorin has moderately strong PknG inhibitory activity, but no cytotoxicity, and it could substantially decrease the growth of mycobacterium tuberculosis inside macrophages. | 28237032 |
| 2017-10-21 10:54:00 | Data suggest PknG is necessary in Mycobacterium tuberculosis for efficient metabolic adaptation during stress such as exposure to antibiotics and hypoxic environment; PknG-mediated GarA phosphorylation is important for maintenance of both mycobacterial physiology and redox poise. (PknG = protein kinase G; GarA = glycogen accumulation regulator) | 28821621 |
| 2017-10-07 12:31:00 | GarA is a cellular target of PknG and the metabolomics data demonstrate that the function of this signaling system is in metabolic regulation. | 28545104 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PKNG_MYCTU
UniprotKB:
P9WI73
UniParc:
UPI0000131B7D
EMBL:
AL123456
EnsemblGenome:
Rv0410c
KO:
mtv:RVBD_0410c,
mtu:Rv0410c
|
| Nucleutide sequences |
EMBL-CDS:
CCP43141.1
Gene_ORFName:
MTCY22G10.06c
EnsemblGenome_TRS:
CCP43141
|
| Protein sequencees |
EnsemblGenome_PRO:
CCP43141
|
| Others |
UniRef100:
UniRef100_P65729
UniRef90:
UniRef90_P65729
UniRef50:
UniRef50_A0QQK3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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