| Type | Description |
|---|---|
| Definition | LIM domain binding 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:48:00 | LDB1 Enforces Stability on Direct and Indirect Oncoprotein Partners in Leukemia. | 32229578 |
| 2020-04-18 11:43:00 | LDB1 dimerization supports long-range connections between enhancers and genes involved in erythropoiesis, including the beta-globin genes. Single-stranded DNA binding proteins (SSBPs) interact specifically with the LDB/Chip conserved domain (LCCD) of LDB proteins and stabilize LDBs by preventing their proteasomal degradation, thus promoting their functions in gene regulation. | 31892537 |
| 2018-03-10 11:10:00 | Data indicate that LIM-domain-binding protein 1 (LDB1) has a strong role in colorectal cancer (CRC) progression. | 27713177 |
| 2017-09-09 12:46:00 | LDB1 maintains the terminally differentiated state of beta cells and is a component of active enhancers in both murine and human islets. | 27941246 |
| 2016-09-24 12:18:00 | SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic beta-Cell Target Genes | 26495868 |
| Type | IDs |
|---|---|
| Synonymous | CLIM-2, CLIM2, LDB-1, NLI |
| Gene |
UniProtKB-ID:
LDB1_HUMAN,
A0A6E1WJ75_HUMAN
UniprotKB:
Q86U70,
A0A6E1WJ75
UniParc:
UPI00001F95E9,
UPI0000000C9D,
UPI00001F95EA,
UPI0000D83536
EMBL:
BT007054,
AJ243098,
AL500527,
CH471066,
AB250384,
BC000482,
AB016485,
AF068652,
AK300588,
AF064491,
BC009246
Ensembl:
ENSG00000198728
KO:
hsa:8861
|
| Nucleutide sequences |
EMBL-CDS:
AAH09246.1,
BAG62286.1,
AAP35703.1,
AAH00482.1,
AAC77818.1,
CAB45409.1,
BAA31991.1,
BAE95402.1,
AAC28341.1,
EAW49724.1
Gene_ORFName:
hCG_25635
Ensembl_TRS:
ENST00000361198,
ENST00000673968,
ENST00000425280
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000501277,
ENSP00000354616,
ENSP00000392466
RefSeq:
NP_003884.1,
NP_001308541.1,
XP_016872356.1,
XP_016872358.1,
XP_016872357.1,
NP_001106878.1
|
| Others |
UniRef100:
UniRef100_Q86U70,
UniRef100_A0A6E1WJ75
UniRef90:
UniRef90_D3Z1C5,
UniRef90_Q86U70
UniRef50:
UniRef50_Q86U70,
UniRef50_A0A674H6M7
UniGene:
Hs.454418
CCDS:
CCDS44472.1,
CCDS7528.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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