| Type | Description |
|---|---|
| Definition | nucleoside diphosphate kinase |
| Date | Results | Publications |
|---|---|---|
| 2014-02-22 12:26:00 | Data suggest Ndk contributes to virulence of Mycobacterium tuberculosis via attenuation of NADPH oxidase-mediated host innate immunity; Ndk binds to/inactivates small GTPase Rac1 (RAS-related C3 botulinum substrate 1) in macrophages. | 23874203 |
| 2013-09-21 12:37:00 | The quaternary structure of nucleoside diphosphate kinase is essential for full enzymatic activity and for protein stability to thermal and chemical denaturation. Identified the intersubunit salt bridge Arg(80)-Asp(93) as essential for hexamer stability. | 23526954 |
| 2010-04-12 11:10:00 | Study presents evidence that PPK2 regulates the intracellular nucleotide pool by interacting with nucleoside diphosphate kinase. | 19843229 |
| 2010-01-21 00:00:00 | In contrast to the robust uracil excision activity reported for E. coli NDK, the Mycobacterium tuberculosis NDK preparation exhibited very poor excision of uracil from DNA. | 15380104 |
| Type | IDs |
|---|---|
| Synonymous | ndk |
| Gene |
UniProtKB-ID:
NDK_MYCTU
UniprotKB:
P9WJH7
UniParc:
UPI000003325E
EMBL:
AL123456
EnsemblGenome:
Rv2445c
KO:
mtu:Rv2445c,
mtv:RVBD_2445c
|
| Nucleutide sequences |
EMBL-CDS:
CCP45238.1
Gene_ORFName:
MTCY428.01,
MTV008.01c
EnsemblGenome_TRS:
CCP45238
|
| Protein sequencees |
EnsemblGenome_PRO:
CCP45238
|
| Others |
UniRef100:
UniRef100_P84283
UniRef90:
UniRef90_P84283
UniRef50:
UniRef50_O85501
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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