Type | Description |
---|---|
Definition | A-kinase anchoring protein 4 |
Date | Results | Publications |
---|---|---|
2020-05-09 13:47:00 | A-kinase anchor protein 4 downregulation inhibits various malignant properties and enhances the cytotoxic effect of paclitaxel, and this combinatorial approach could be useful for triple-negative breast cancer treatment. | 32342732 |
2019-12-21 12:02:00 | Knockdown of AKAP4 inhibits hypoxia-induced epithelial-mesenchymal transition in human gastric cancer cells, at least in part, via inactivation of the Wnt/beta-catenin signaling pathway. | 30145836 |
2019-12-14 12:36:00 | pro-AKAP4 protein in the fibrous sheath of human ejaculated spermatozoa and in elongating/elongated spermatids in the human testis. In normozoospermia, there were high interindividual variations in pro-AKAP4 levels, and these latter were associated with sperm motility. | 29984477 |
2019-09-07 11:25:00 | This study showed the role of Lactobacilli in down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes. Such expression change might be involved in the anticancer effects of these Lactobacilli. The underlying mechanisms of these observations are not clear but epigenetic modulatory mechanisms may participate in this process. | 30545223 |
2018-11-03 11:54:00 | High AKAP4 expression is associated with reduced sperm motility. | 29581387 |
Type | IDs |
---|---|
Synonymous | AKAP 82, AKAP-4, AKAP82, CT99, FSC1, HI, PRKA4, hAKAP82, p82 |
Gene |
UniProtKB-ID:
AKAP4_HUMAN,
A0A384MQY7_HUMAN
UniprotKB:
Q5JQC9,
A0A384MQY7
UniParc:
UPI000013DA96,
UPI0000161A4C
EMBL:
CH471180,
Y15195,
FO393402,
GQ891359,
BC126252,
AF072756,
BC126250
Ensembl:
ENSG00000147081
KO:
hsa:8852
|
Nucleutide sequences |
EMBL-CDS:
CAA75494.1,
AAI26251.1,
AAI26253.1,
AAC79433.1,
EAW89926.1,
ADO22221.1
Gene_ORFName:
hCG_1993017
Ensembl_TRS:
ENST00000358526,
ENST00000376064
|
Protein sequencees |
Ensembl_PRO:
ENSP00000365232,
ENSP00000351327
RefSeq:
NP_647450.1,
NP_003877.2
|
Others |
UniRef100:
UniRef100_Q5JQC9
UniRef90:
UniRef90_Q5JQC9
UniRef50:
UniRef50_Q60662
UniGene:
Hs.97633
CCDS:
CCDS14330.1,
CCDS14329.1
|
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Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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