| Type | Description |
|---|---|
| Definition | pantothenate kinase |
| Date | Results | Publications |
|---|---|---|
| 2018-07-07 11:48:00 | The results presented here suggest that comparatively small structural perturbations are sufficient to convert MtPanK into an enzyme with features similar to those of E coli PanK. In addition to the intended effect of weakening the binding to CoA, the mutants exhibit a somewhat lower activity compared with the wild-type enzyme, in a manner that is explainable in terms of their structures. | 29095158 |
| 2013-09-07 10:37:00 | Studies determined structures of M. tuberculosis PanK (MtPanK; coaA; Rv1092c) complexed with inhibitors. | 23661699 |
| 2011-01-01 10:53:00 | CoaA (Rv1092c) is essential for the survival of M. tuberculosis. | 20576686 |
| 2010-07-05 12:05:00 | Results examine the dual substrate specificity for ATP and GTP and unusual changes in ligand locations of M. tuberculosis pantothenate kinase. | 20451532 |
| 2010-01-21 00:00:00 | The enzyme from Mycobacterium tuberculosis, MW 35.7 kDa, has been cloned, expressed, purified and crystallized in two different trigonal crystal forms. | 16508093 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
COAA_MYCTU
UniprotKB:
P9WPA7
UniParc:
UPI0000038DDA
EMBL:
AL123456
EnsemblGenome:
Rv1092c
KO:
mtv:RVBD_1092c,
mtu:Rv1092c
|
| Nucleutide sequences |
EMBL-CDS:
CCP43845.1
Gene_ORFName:
MTV017.45c
EnsemblGenome_TRS:
CCP43845
|
| Protein sequencees |
EnsemblGenome_PRO:
CCP43845
|
| Others |
UniRef100:
UniRef100_P63811
UniRef90:
UniRef90_B2HT62
UniRef50:
UniRef50_Q8NRQ2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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