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8851 CDK5R1

8851

CDK5R1

cyclin dependent kinase 5 regulatory subunit 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition cyclin dependent kinase 5 regulatory subunit 1

研究结论

Date Results Publications
2020-08-29 12:44:00 The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication. 30718749
2018-11-03 10:58:00 Study demonstrated that NEAT1 and HOTAIR negatively regulate CDK5R1 mRNA levels, while MALAT1 has a positive effect. 29997370
2018-05-12 10:30:00 the downregulation of the miR-15/107 family might have a role in the pathogenesis of AD by increasing the levels of CDK5R1/p35 and consequently enhancing CDK5 activity. 27343180
2017-05-20 14:54:00 It is shown that p5 binds the kinase at the same CDK5/p25 and CDK5/p35 interfaces, and is thus a non-selective competitor of both activators, in agreement with available experimental data in vitro. 27387995
2017-04-01 10:41:00 the minor allele of CDK5R1 3'-UTR rs735555 polymorphism was associated with increased risk for NS-ID. In conclusion, our data suggest that mutations and polymorphisms in CDK5 and CDK5R1 genes may contribute to the onset of the NS-ID phenotype 26657932

名称对应

Type IDs
Synonymous CDK5P35, CDK5R, NCK5A, p23, p25, p35, p35nck5a
Gene
UniProtKB-ID: CD5R1_HUMAN, Q8N619_HUMAN
UniprotKB: Q15078, Q8N619
UniParc: UPI000012738E, UPI0000070F4D
EMBL: AY376350, BC030792, CH471147, BT019573, BC020580, X80343
Ensembl: ENSG00000176749
KO: hsa:8851
Nucleutide sequences
EMBL-CDS: AAV38380.1, EAW80227.1, AAQ74776.1, CAA56587.1, EAW80228.1, AAH20580.1, AAH30792.1
Ensembl_TRS: ENST00000313401
Protein sequencees
Ensembl_PRO: ENSP00000318486
RefSeq: XP_011523740.1, NP_003876.1, XP_016880770.1
Others
UniRef100: UniRef100_Q15078, UniRef100_Q8N619
UniRef90: UniRef90_Q15078
UniRef50: UniRef50_Q15078
UniGene: Hs.500015
CCDS: CCDS11273.1

全选

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