| Type | Description |
|---|---|
| Definition | TSC22 domain family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-14 10:33:00 | TSC22 could suppress tumor by inhibiting cell proliferation in colorectal cancer cell lines. Multivariate Cox regression analysis confirmed TSC22 expression as independent predictors of the OS in CRC patients | 29481799 |
| 2013-02-23 10:55:00 | TSC-22 acts as a tumor suppressor by safeguarding p53 from poly-ubiquitination mediated-degradation. | 22870275 |
| 2012-03-24 11:47:00 | we report that induced Tsc-22 leads to enhancement of TGF-beta-dependent signaling and enhancement is blocked by expression of a dominant-negative Tsc-22 mutant | 21881999 |
| 2011-07-09 10:59:00 | Differential regulation of antagonistic TSC22D1 variants is required for the establishment of oncogene-induced cellular senescence. | 21448135 |
| 2011-01-15 10:49:00 | Results support role of TSC22D1 as an enhancer of CNP transcription and suggest that TGF-beta-induced upregulation of CNP expression in smooth muscle may be mediated in part by increased transcription of TSC22D1. | 20802130 |
| Type | IDs |
|---|---|
| Synonymous | Ptg-2, TGFB1I4, TSC22 |
| Gene |
UniProtKB-ID:
T22D1_HUMAN,
A0A087X0H8_HUMAN,
A0A024RDV8_HUMAN,
A8K3Y6_HUMAN
UniprotKB:
Q15714,
A0A087X0H8,
A0A024RDV8,
A8K3Y6
UniParc:
UPI0000372314,
UPI00001FCCF6,
UPI00015DA764,
UPI00017BE7B3,
UPI0000D61A6B,
UPI0000137728
EMBL:
BC136475,
AK091854,
AJ222700,
AF256226,
CH471075,
CR627459,
BC146679,
AL139184,
AL138960,
BC069207,
AK290751,
D38585,
AK312345,
U35048,
CR456711,
AB082525,
BC105277,
BC000456,
BC016867,
KF455773,
D87061,
AL356107,
BC146664,
BC136482
Ensembl:
ENSG00000102804
KO:
hsa:8848
|
| Nucleutide sequences |
EMBL-CDS:
BAG35266.1,
AAG53077.1,
AAI36476.1,
AAH69207.1,
AAH00456.1,
BAA07598.1,
BAC02703.1,
AAI46680.1,
CAA10951.1,
AAI36483.1,
CAH10539.1,
AAH16867.1,
AAC50566.1,
BAB46917.1,
BAG52429.1,
EAX08710.1,
AAI46665.1,
CAG32992.1,
AAI05278.1,
EAX08711.1,
BAF83440.1
Gene_ORFName:
hucep-2,
hCG_32172
Ensembl_TRS:
ENST00000261489,
ENST00000458659,
ENST00000501704,
ENST00000611198,
ENST00000622051
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261489,
ENSP00000437414,
ENSP00000397435,
ENSP00000481585,
ENSP00000483407
RefSeq:
NP_001230726.1,
NP_904358.2,
XP_016876299.1,
NP_006013.1,
NP_001230728.1,
NP_001230727.1,
XP_005266640.1,
XP_016876300.1,
XP_024305195.1
|
| Others |
UniRef100:
UniRef100_A8K3Y6,
UniRef100_Q15714,
UniRef100_Q3MHL6,
UniRef100_A0A087X0H8
UniRef90:
UniRef90_P62501,
UniRef90_Q15714,
UniRef90_Q5R4H1
UniRef50:
UniRef50_Q5R4H1,
UniRef50_P62501,
UniRef50_P62500
UniGene:
Hs.436383
CCDS:
CCDS58291.1,
CCDS31966.1,
CCDS9392.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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