| Type | Description |
|---|---|
| Definition | alkB homolog 1, histone H2A dioxygenase |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:02:00 | ALKBH1 deficiency leads to loss of homeostasis in human diploid somatic cells. | 32661925 |
| 2020-10-31 13:19:00 | MiRNA-339-5p suppresses the malignant development of gastric cancer via targeting ALKBH1. | 32380054 |
| 2020-07-25 10:06:00 | Downregulation of Alkbh1 impacts cell growth in HeLa cells and delays development in Caenorhabditis elegans, where the mitochondrial role of Alkbh1 seems to be conserved. | 31434717 |
| 2020-01-04 12:06:00 | AlkB homologue 1 (ALKBH1) was capable of demethylating m(3)C in mRNA of mammalian cells in vitro. Overexpression and knockdown of ALKBH1 in cultured human cells can induce decrease and increase of the level of m(3)C in mRNA, respectively, revealing the eraser enzyme property of ALKBH1 on m(3)C in mRNA. | 31188562 |
| 2019-11-30 10:54:00 | Data show that the three DNA repair enzymes ALKBH2, ALKBH3, and AlkB are not only able to repair DNA adducts, but also can edit the epigenetic modification and generate the corresponding oxidative derivatives. | 31114894 |
| Type | IDs |
|---|---|
| Synonymous | ABH, ABH1, ALKBH, alkB, hABH |
| Gene |
UniProtKB-ID:
ALKB1_HUMAN,
Q5XKL0_HUMAN
UniprotKB:
Q13686,
Q5XKL0
UniParc:
UPI000012585D,
UPI00004432ED
EMBL:
AC008044,
X91992,
BC025787,
BC015024
Ensembl:
ENSG00000100601
KO:
hsa:8846
|
| Nucleutide sequences |
EMBL-CDS:
AAF01478.1,
CAA63047.1,
AAH25787.1,
AAH15024.1
Ensembl_TRS:
ENST00000216489
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216489
RefSeq:
NP_006011.2
|
| Others |
UniRef100:
UniRef100_Q5XKL0,
UniRef100_Q13686
UniRef90:
UniRef90_Q13686
UniRef50:
UniRef50_Q13686
UniGene:
Hs.94542
CCDS:
CCDS32127.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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