| Type | Description |
|---|---|
| Definition | cellular communication network factor 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:30:00 | CCN5 inhibits proliferation and promotes apoptosis of oral squamous cell carcinoma cells. | 31889370 |
| 2019-06-15 10:55:00 | Our findings suggest that activation of WISP2 could be a useful therapeutic strategy for the treatment of esophageal squamous cell carcinoma | 30808397 |
| 2018-09-08 10:08:00 | The authors show that, in triple-negative-breast cancer (TNBC) cells enriched with tumor initiating cells, CCN5 significantly blocks cellular growth via apoptosis, reversing epithelial-mesenchymal-transition-signaling and impairing mammosphere formation, thereby blocking the tumor-forming ability and invasive capacity of these cells. | 28450698 |
| 2018-08-18 11:49:00 | by analyzing different estrogen receptor-alpha(ER-a)-positive and ER-a-negative breast cancer cell lines, we defined the role of CCN5 in the leptin-mediated regulation of growth and invasive capacity. | 29370782 |
| 2018-01-06 12:29:00 | CCN3 (Nov) and CCN5 (WISP2) are novel substrates of MMP14. | 27471094 |
| Type | IDs |
|---|---|
| Synonymous | CT58, CTGF-L, WISP2 |
| Gene |
UniProtKB-ID:
CCN5_HUMAN
UniprotKB:
O76076
UniParc:
UPI0000037219,
UPI00001CE06D
EMBL:
AF100780,
AY358915,
CH471077,
BC017782,
BC064379,
AF083500,
AL139352,
AK313853,
BC058074,
AF074604
Ensembl:
ENSG00000064205
KO:
hsa:8839
|
| Nucleutide sequences |
EMBL-CDS:
BAG36581.1,
EAW75903.1,
AAC70350.1,
AAQ89274.1,
AAH17782.1,
AAH58074.1,
EAW75902.1,
AAH64379.1,
AAC26794.1,
AAC96322.1
Gene_ORFName:
UNQ228/PRO261
Ensembl_TRS:
ENST00000190983,
ENST00000372868,
ENST00000372865
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361959,
ENSP00000190983,
ENSP00000361956
RefSeq:
XP_016883606.1,
NP_003872.1,
XP_016883605.1,
NP_001310298.1,
NP_001310299.1
|
| Others |
UniRef100:
UniRef100_O76076
UniRef90:
UniRef90_O76076
UniRef50:
UniRef50_O76076
UniGene:
Hs.592145
CCDS:
CCDS13336.1,
CCDS82619.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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