Type | Description |
---|---|
Definition | isocitrate lyase |
Date | Results | Publications |
---|---|---|
2019-09-14 10:14:00 | Expression of aceA gene, encoding isocitrate lyase (ICL), in Pseudomonas aeruginosa is upregulated under H2O2-induced oxidative stress and under iron-limiting conditions. The enzymatic activities of ICL and isocitrate dehydrogenase have opposite responses under different iron conditions, suggesting that the glyoxylate shunt (GS) is important under iron-limiting conditions. | 29465342 |
2013-11-23 11:17:00 | These results indicated that the N214 residue is essential for catalytic function, while mutating the Q211, E219, and Q221 residues impairs its catalytic and thermostability properties. | 23338961 |
2010-07-19 12:23:00 | RpoN negatively regulates aceA activity. | 20093293 |
2010-01-21 00:00:00 | The PAO1 isocitrate lyase (ICL) mutant was less virulent in the rat lung infection model, indicating that ICL is required for the pathogenesis of P. aeruginosa in mammals | 18524916 |
2010-01-21 00:00:00 | AceA gene encodes isocitrate lyase involved in the assimilation of acetate, acyclic monoterpenes of the citronellol family, alkanols, and leucine, in which the final intermediary acetyl-coenzyme A may be channelled to the glyoxylate shunt. | 17319879 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
ACEA_PSEAE
UniprotKB:
Q9I0K4
UniParc:
UPI00000C577B
EMBL:
AE004091
EnsemblGenome:
PA2634
KO:
pae:PA2634
|
Nucleutide sequences |
EMBL-CDS:
AAG06022.1
EnsemblGenome_TRS:
AAG06022
|
Protein sequencees |
EnsemblGenome_PRO:
AAG06022
RefSeq:
NP_251324.1
|
Others |
UniRef100:
UniRef100_Q9I0K4
UniRef90:
UniRef90_Q9I0K4
UniRef50:
UniRef50_O50078
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
29465342 |
Lack of glyoxylate shunt dysregulates iron homeostasis in Pseudomonas aeruginosa. Microbiology (Reading, Engl.) Sunhee Ha , Bora Shin , Woojun Park |
2018-04-01 | - |
23338961 |
World J. Microbiol. Biotechnol. Jesus Campos-Garcia , Cesar Diaz-Perez , Alma Laura Diaz-Perez |
2013-06-01 | - |
20093293 |
Influence of RpoN on isocitrate lyase activity in Pseudomonas aeruginosa. Microbiology (Reading, Engl.) Jessica M Hagins , Jessica A Scoffield , Sang-Jin Suh , Laura Silo-Suh |
2010-04-01 | - |
19700524 |
J Bacteriol Jessica M Hagins , Robert Locy , Laura Silo-Suh |
2009-10-01 | - |
18978025 |
Nucleic Acids Res. Geoffrey L Winsor , Thea Van Rossum , Raymond Lo , Bhavjinder Khaira , Matthew D Whiteside , Robert E W Hancock , Fiona S L Brinkman |
2009-01-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
18524916 |
Microbiology (Reading, Engl.) Tamishia L Lindsey , Jessica M Hagins , Pamela A Sokol , Laura A Silo-Suh |
2008-06-01 | - |
17319879 |
FEMS Microbiol. Lett. Alma Laura DÃaz-Pérez , Celinda Román-Doval , César DÃaz-Pérez , Carlos Cervantes , Carlos R Sosa-Aguirre , Joel E López-Meza , Jesús Campos-GarcÃa |
2007-04-01 |
aceA
|
17015649 |
J. Bacteriol. Ryan T Cirz , Bryan M O'Neill , Jennifer A Hammond , Steven R Head , Floyd E Romesberg |
2006-10-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
16030221 |
Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. J. Bacteriol. Kelli L Palmer , Lauren M Mashburn , Pradeep K Singh , Marvin Whiteley |
2005-08-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
15995206 |
J. Bacteriol. Prabhakar Salunkhe , Catherine H M Smart , J Alun W Morgan , Stavroula Panagea , Martin J Walshaw , C Anthony Hart , Robert Geffers , Burkhard Tümmler , Craig Winstanley |
2005-07-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
排名 | 科研单位 | 文献 |
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