fleQ - transcriptional regulator FleQ-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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881960 fleQ

基因描述

Type	Description
Definition	transcriptional regulator FleQ

研究结论

Date	Results	Publications
2020-01-04 11:31:00	This study determined the crystal structures of the ATPase domain of wild-type FleQ and sensor I mutants H287N and H287A in complex with ATPgammaS and Mg(2+) to 2.4, 1.95, and 2.25 A resolution, respectively.	31268665
2019-01-26 11:13:00	FleQ mutation prevented flagellar assembly and reduced internalization of Pseudomonas aeruginosa independently of ExoS.	29717012
2017-10-07 12:42:00	The dimer is the functional form of FleN, and it is nucleotide binding and not hydrolysis by FleN that is necessary to exert an antagonistic effect against FleQ.	28065505
2016-07-30 11:08:00	The atypical REC domain of FleQ is essential for the function of FleQ.	26362077
2015-01-10 13:32:00	The ability of FleQ to positively regulate flagellar gene expression.	24827992

名称对应

Type	IDs
Gene	UniProtKB-ID: FLEQ_PSEAE UniprotKB: G3XCV0 UniParc: UPI00000D421B EMBL: AE004091 EnsemblGenome: PA1097 KO: pae:PA1097
Nucleutide sequences	EMBL-CDS: AAG04486.1 EnsemblGenome_TRS: AAG04486
Protein sequencees	EnsemblGenome_PRO: AAG04486 RefSeq: NP_249788.1
Others	UniRef100: UniRef100_G3XCV0 UniRef90: UniRef90_G3XCV0 UniRef50: UniRef50_G3XCV0

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
31268665	Sensor I Regulated ATPase Activity of FleQ Is Essential for Motility to Biofilm Transition in Pseudomonas aeruginosa. ACS Chem. Biol. Priyajit Banerjee , Chanchal , Deepti Jain	2019-07-19	-
29717012	The Impact of ExoS on Pseudomonas aeruginosa Internalization by Epithelial Cells Is Independent of fleQ and Correlates with Bistability of Type Three Secretion System Gene Expression. mBio Abby R Kroken , Camille K Chen , David J Evans , Timothy L Yahr , Suzanne M J Fleiszig	2018-05-01	-
28065505	ATP-Induced Structural Remodeling in the Antiactivator FleN Enables Formation of the Functional Dimeric Form. Structure Chanchal , Priyajit Banerjee , Deepti Jain	2017-02-07	-
26362077	The REC domain mediated dimerization is critical for FleQ from Pseudomonas aeruginosa to function as a c-di-GMP receptor and flagella gene regulator. J. Struct. Biol. Tiantian Su , Shiheng Liu , Kang Wang , Kaikai Chi , Deyu Zhu , Tiandi Wei , Yan Huang , Liming Guo , Wei Hu , Sujuan Xu , Zong Lin , Lichuan Gu	2015-10-01	-
24827992	A conservative amino acid mutation in the master regulator FleQ renders Pseudomonas aeruginosa aflagellate. PLoS One Ruchi Jain , Barbara I Kazmierczak	2014-01-01	-
24167275	Cyclic diguanosine monophosphate represses bacterial flagella synthesis by interacting with the Walker A motif of the enhancer-binding protein FleQ. Proc. Natl. Acad. Sci. U.S.A. Claudine Baraquet , Caroline S Harwood	2013-11-12	fleQ
22581773	The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response to c-di-GMP. Nucleic Acids Res. Claudine Baraquet , Keiji Murakami , Matthew R Parsek , Caroline S Harwood	2012-08-01	fleQ
18978025	Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Nucleic Acids Res. Geoffrey L Winsor , Thea Van Rossum , Raymond Lo , Bhavjinder Khaira , Matthew D Whiteside , Robert E W Hancock , Fiona S L Brinkman	2009-01-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
18485075	Identification of FleQ from Pseudomonas aeruginosa as a c-di-GMP-responsive transcription factor. Mol. Microbiol. Jason W Hickman , Caroline S Harwood	2008-07-01	fleQ
17015649	Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. J. Bacteriol. Ryan T Cirz , Bryan M O'Neill , Jennifer A Hammond , Steven R Head , Floyd E Romesberg	2006-10-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341

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