| Type | Description |
|---|---|
| Definition | acyl-homoserine-lactone synthase |
| Date | Results | Publications |
|---|---|---|
| 2013-07-06 11:18:00 | Subinhibitory concentrations of macrolides specifically upregulated expression of quorum sensing genes (rhlR, lasI), whereas sulfonamides and municipal wastewater, instead upregulated expression of specific resistant genes (sul1) and efflux pumps (mexD). | 23392972 |
| 2010-01-21 00:00:00 | The quorum-sensing lasI and rhlI genes in Ps. aeruginosa affect acute prostate infections, but play a considerably more important role in maintaining chronic infections. | 19460822 |
| 2010-01-21 00:00:00 | Data found that Lon represses the expression of LasR/LasI by degrading LasI, an HSL synthase, leading to negative regulation of the RhlR/RhlI system. | 18408026 |
| 2010-01-21 00:00:00 | Transcription remained more constant throughout the lung infection. | 15668029 |
| 2010-01-21 00:00:00 | artificially increasing lasI transcript levels leads to higher levels of 3OC12HSL. | 17559399 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LASI_PSEAE
UniprotKB:
P33883
UniParc:
UPI000012E230
EMBL:
AE004091,
L04681
EnsemblGenome:
PA1432
KO:
pae:PA1432
|
| Nucleutide sequences |
EMBL-CDS:
AAG04821.1,
AAA25875.1
EnsemblGenome_TRS:
AAG04821
|
| Protein sequencees |
EnsemblGenome_PRO:
AAG04821
RefSeq:
NP_250123.1
|
| Others |
UniRef100:
UniRef100_P33883
UniRef90:
UniRef90_P33883
UniRef50:
UniRef50_P33883
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 23392972 |
Environ Sci Pollut Res Int Julia Bruchmann , Silke Kirchen , Thomas Schwartz |
2013-06-01 | - |
| 19460822 |
Microbiology (Reading, Engl.) Lisa K Nelson , Genevieve H D'Amours , Kimberley M Sproule-Willoughby , Douglas W Morck , Howard Ceri |
2009-08-01 | - |
| 18978025 |
Nucleic Acids Res. Geoffrey L Winsor , Thea Van Rossum , Raymond Lo , Bhavjinder Khaira , Matthew D Whiteside , Robert E W Hancock , Fiona S L Brinkman |
2009-01-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 18408026 |
J. Bacteriol. Akiko Takaya , Fumiaki Tabuchi , Hiroko Tsuchiya , Emiko Isogai , Tomoko Yamamoto |
2008-06-01 |
lon,
rhlI,
rhlR,
lasI,
lasR
|
| 17559399 |
FEMS Microbiol. Lett. Matthew J Wargo , Deborah A Hogan |
2007-08-01 |
lasI,
lasR
|
| 17367209 |
Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa. PLoS Pathog. Olga Zaborina , Francois Lepine , Gaoping Xiao , Vesta Valuckaite , Yimei Chen , Terry Li , Mae Ciancio , Alex Zaborin , Elaine O Petrof , Elaine Petroff , Jerrold R Turner , Laurence G Rahme , Eugene Chang , John C Alverdy |
2007-03-01 |
rhlI,
rhlR,
mvfR,
gacA,
lasI,
lasR,
gltA,
lecA
|
| 17015649 |
J. Bacteriol. Ryan T Cirz , Bryan M O'Neill , Jennifer A Hammond , Steven R Head , Floyd E Romesberg |
2006-10-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 16030221 |
Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. J. Bacteriol. Kelli L Palmer , Lauren M Mashburn , Pradeep K Singh , Marvin Whiteley |
2005-08-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 15995206 |
J. Bacteriol. Prabhakar Salunkhe , Catherine H M Smart , J Alun W Morgan , Stavroula Panagea , Martin J Walshaw , C Anthony Hart , Robert Geffers , Burkhard Tümmler , Craig Winstanley |
2005-07-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 15908409 |
Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Infect. Immun. M J Filiatrault , V E Wagner , D Bushnell , C G Haidaris , B H Iglewski , L Passador |
2005-06-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员