gacS - sensor/response regulator hybrid protein-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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880882 gacS

基因描述

Type	Description
Definition	sensor/response regulator hybrid protein

研究结论

Date	Results	Publications
2021-01-16 15:56:00	A revised model for the role of GacS/GacA in regulating type III secretion by Pseudomonas syringae pv. tomato DC3000.	31588661
2020-06-13 10:04:00	x-ray crystallography reveals that RetS uses the reversible unfolding of a helix, or helix cracking, to control interactions with GacS	30879888
2018-12-22 11:55:00	Study interactions between two sensor kinases from Pseudomonas aeruginosa, GacS and RetS, which control the switch between acute and chronic virulence demonstrate three mechanisms by which RetS attenuates GacS signalling: RetS takes phosphoryl groups from GacS-P; RetS has transmitter phosphatase activity against the receiver domain of GacS-P; and RetS inhibits GacS autophosphorylation.	29880803
2017-05-13 20:21:00	LadS HK thus forms, with the GacS/GacA TCS, a multicomponent signal transduction system with an original phosphorelay cascade, i.e. H1LadS-->D1LadS-->H2GacS-->D2GacA.	27176226
2010-01-21 00:00:00	The GacS/GacA system transduces the regulatory signals to downstream genes exclusively by directly controlling the expression of only two genes rsmY and rsmZ.	19602144

名称对应

Type	IDs
Gene	UniProtKB-ID: G3XD98_PSEAE, O31138_PSEAI UniprotKB: G3XD98, O31138 UniParc: UPI00000D428B EMBL: QORE01000125, RWPP01000009, RXTB01000092, RWMJ01000013, AE004091, LT969520, AF030352, LTQU01000047, RWQP01000001, RWUZ01000002, RWTJ01000009, NFFZ01000005, RWNG01000003, RWOM01000006, NSVB01000021, RHMD02000002 EnsemblGenome: PA0928, PAERUG_E15_London_28_01_14_01984 KO: pae:PA0928
Nucleutide sequences	EMBL-CDS: AAG04317.1, OTI62219.1, RCI75754.1, OHP17687.1, RPY64678.1, TEE17689.1, TEH34156.1, AAB86557.1, RTR72404.1, TEO89794.1, TEJ09047.1, TEF47450.1, TER57098.1, TEK66189.1, TGB22402.1, SOV31132.1 Gene_ORFName: IPC36_07310, CAZ10_11630, HMPREF2687_19890, IPC1509_25465, IPC620_28120, ECC04_024475, IPC582_05115, DY930_19140, IPC669_29690, RW109_RW109_05256, IPC116_20880, DT376_05980, IPC1481_06080, IPC1323_16185
Protein sequencees	RefSeq: NP_249619.1
Others	UniRef100: UniRef100_G3XD98 UniRef90: UniRef90_G3XD98 UniRef50: UniRef50_P48027

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mRNA

Protein

UniprotKB

Description

Refseq

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Ensembl: {{protein.nucleotideEnsembl}}

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Ensembl: {{protein.proteinEnsembl}}

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Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

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Pubmed编号	文献信息	发表日期	相关基因
31588661	A revised model for the role of GacS/GacA in regulating type III secretion by Pseudomonas syringae pv. tomato DC3000. Mol Plant Pathol Megan R O'Malley , Ching-Fang Chien , Scott C Peck , Nai-Chun Lin , Jeffrey C Anderson	2020-01-01	-
30879888	Helix Cracking Regulates the Critical Interaction between RetS and GacS in Pseudomonas aeruginosa. Structure Jordan M Mancl , William K Ray , Rich F Helm , Florian D Schubot	2019-05-07	-
29880803	Multiple communication mechanisms between sensor kinases are crucial for virulence in Pseudomonas aeruginosa. Nat Commun Vanessa I Francis , Elaine M Waters , Sutharsan E Finton-James , Andrea Gori , Aras Kadioglu , Alan R Brown , Steven L Porter	2018-06-07	-
27176226	The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa. PLoS Genet. GaÃ«l Chambonnier , LorÃ¨ne Roux , David Redelberger , Firas Fadel , Alain Filloux , Melissa Sivaneson , Sophie de Bentzmann , Christophe Bordi	2016-05-01	-
19602144	The GacS/GacA signal transduction system of Pseudomonas aeruginosa acts exclusively through its control over the transcription of the RsmY and RsmZ regulatory small RNAs. Mol Microbiol Anja Brencic , Kirsty A McFarland , Heather R McManus , Sandra Castang , Ilaria Mogno , Simon L Dove , Stephen Lory	2009-08-01	-
18978025	Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Nucleic Acids Res. Geoffrey L Winsor , Thea Van Rossum , Raymond Lo , Bhavjinder Khaira , Matthew D Whiteside , Robert E W Hancock , Fiona S L Brinkman	2009-01-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
17015649	Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. J. Bacteriol. Ryan T Cirz , Bryan M O'Neill , Jennifer A Hammond , Steven R Head , Floyd E Romesberg	2006-10-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
16030221	Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. J. Bacteriol. Kelli L Palmer , Lauren M Mashburn , Pradeep K Singh , Marvin Whiteley	2005-08-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
15995206	A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. J. Bacteriol. Prabhakar Salunkhe , Catherine H M Smart , J Alun W Morgan , Stavroula Panagea , Martin J Walshaw , C Anthony Hart , Robert Geffers , Burkhard TÃ¼mmler , Craig Winstanley	2005-07-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
15908409	Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Infect. Immun. M J Filiatrault , V E Wagner , D Bushnell , C G Haidaris , B H Iglewski , L Passador	2005-06-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341

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