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879837 exoS

879837

exoS

exoenzyme S

protein-coding

Pseudomonas aeruginosa PAO1

基因描述

Type Description
Definition exoenzyme S

研究结论

Date Results Publications
2020-11-21 13:34:00 High frequency of the exoU+/exoS+ genotype associated with multidrug-resistant ""high-risk clones"" of Pseudomonas aeruginosa clinical isolates from Peruvian hospitals. 31350412
2019-10-26 10:54:00 Data provide compelling evidence showing that ExoS/GAP domain is necessary and sufficient to cause intrinsic (mitochondrial) apoptosis. While the low-level of ExoS-induced cytotoxicity that occurs early (within 5 h post-infection) is primarily due to the ADPRT domain activity, the GAP domain is a major contributor to ExoS-induced apoptosis at later time (15-20 h) when ExoS-induced cytotoxicity reaches its maximum level. 30232373
2019-09-14 10:52:00 Epithelial cell lysates induce exoS and exoT gene transcription in P. aeruginosa PAO1. 29518189
2019-01-26 11:13:00 Inhibition of internalization of Pseudomonas aeruginosa was associated with T3SS hyperinducibility and ExoS activity. 29717012
2018-01-20 10:50:00 e present an optimized method to screen for inhibitors of ExoS activity that is amenable to high-throughput format and an intermediate affinity inhibitor that can serve both as assay control and as a starting point for further development 26850638

名称对应

Type IDs
Gene
UniProtKB-ID: EXOS_PSEAE
UniprotKB: G3XDA1
UniParc: UPI00000D4767
EMBL: AE004091
EnsemblGenome: PA3841
KO: pae:PA3841
Nucleutide sequences
EMBL-CDS: AAG07228.1
EnsemblGenome_TRS: AAG07228
Protein sequencees
EnsemblGenome_PRO: AAG07228
RefSeq: NP_252530.1
Others
UniRef100: UniRef100_G3XDA1
UniRef90: UniRef90_G3XDA1
UniRef50: UniRef50_G3XDA1

全选

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研究热度

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