| Type | Description |
|---|---|
| Definition | adenylate cyclase |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 11:44:00 | Our results suggest that the nucleotidyl cyclase activity of ExoY can contribute to P. aeruginosa acute pathogenicity. | 29734720 |
| 2017-09-09 12:26:00 | Here, we report that Pseudomonas aeruginosa ExoY inhibits proinflammatory cytokine production through suppressing the activation of TAK1 as well as downstream NF-kappaB and mitogen-activated protein (MAP) kinases. | 28652310 |
| 2014-09-27 10:59:00 | Thus, ExoY is a nucleotidyl cyclase with preference for cGMP and cUMP production | 24971548 |
| 2011-12-31 11:26:00 | Adenylate cyclase activity of ExoY mediates bleb-niche formation in epithelial cells and contributes to virulence. | 21843628 |
| 2010-01-21 00:00:00 | actin disruption of epithelial cells at 2 h post-infection associated with both adenylate cyclase-active ExoY and its catalytic mutant form ExoYK81M, and which coincided with inhibition of bacterial invasion | 16039071 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q9I1S4_PSEAE
UniprotKB:
Q9I1S4
UniParc:
UPI00000C55FB
EMBL:
AE004091
EnsemblGenome:
PA2191
KO:
pae:PA2191
|
| Nucleutide sequences |
EMBL-CDS:
AAG05579.1
|
| Protein sequencees |
RefSeq:
NP_250881.1
|
| Others |
UniRef100:
UniRef100_A0A6N0ZQ73
UniRef90:
UniRef90_A0A485G9J3
UniRef50:
UniRef50_A0A485G9J3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29734720 |
The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model. Toxins (Basel) Christina Kloth , Bastian Schirmer , Antje Munder , Tane Stelzer , Justin Rothschuh , Roland Seifert |
2018-05-04 | - |
| 28652310 |
Infect. Immun. Chenxi He , Yilong Zhou , Feng Liu , Haipeng Liu , Hao Tan , Shouguang Jin , Weihui Wu , Baoxue Ge |
2017-09-01 | - |
| 24971548 |
Biochem. Biophys. Res. Commun. Urike Beckert , Sabine Wolter , Christina Hartwig , Heike Bähre , Volkhard Kaever , Daniel Ladant , Dara W Frank , Roland Seifert |
2014-07-18 |
exoY
|
| 21843628 |
Microb. Pathog. Victoria Hritonenko , James J Mun , Connie Tam , Nathan C Simon , Joseph T Barbieri , David J Evans , Suzanne M J Fleiszig |
2011-11-01 |
exoY
|
| 18978025 |
Nucleic Acids Res. Geoffrey L Winsor , Thea Van Rossum , Raymond Lo , Bhavjinder Khaira , Matthew D Whiteside , Robert E W Hancock , Fiona S L Brinkman |
2009-01-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 17015649 |
J. Bacteriol. Ryan T Cirz , Bryan M O'Neill , Jennifer A Hammond , Steven R Head , Floyd E Romesberg |
2006-10-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 16039071 |
Actin cytoskeleton disruption by ExoY and its effects on Pseudomonas aeruginosa invasion. FEMS Microbiol. Lett. Brigitte A Cowell , David J Evans , Suzanne M J Fleiszig |
2005-09-01 |
exoY
|
| 16030221 |
Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. J. Bacteriol. Kelli L Palmer , Lauren M Mashburn , Pradeep K Singh , Marvin Whiteley |
2005-08-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 15995206 |
J. Bacteriol. Prabhakar Salunkhe , Catherine H M Smart , J Alun W Morgan , Stavroula Panagea , Martin J Walshaw , C Anthony Hart , Robert Geffers , Burkhard Tümmler , Craig Winstanley |
2005-07-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 15908409 |
Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Infect. Immun. M J Filiatrault , V E Wagner , D Bushnell , C G Haidaris , B H Iglewski , L Passador |
2005-06-01 |
PA2755a,
PA4636a,
PA0032a,
PA0041a,
PA0103a,
PA0306a,
PA0367a,
PA0451a,
PA0701a,
PA0736a,
PA0788a,
PA0951a,
PA1019a,
PA1052a,
PA1112a,
PA1112b,
PA1424a,
PA1428a,
PA1483a,
PA1578a,
PA1643a,
PA1797a,
PA1833a,
PA1837a,
PA1866a,
PA2118a,
PA2142a,
PA2173a,
PA2312a,
PA2559a,
PA2746a,
PA2747a,
PA2750a,
PA2754a,
PA2763a,
PA2772a,
PA3089a,
PA3303a,
PA3403a,
PA3440a,
PA3574a,
PA3733a,
PA3865a,
PA3886a,
PA3963a,
PA3969a,
PA4027a,
PA4108a,
PA4145a,
PA4313a,
PA4360a,
PA4635a,
PA4690a,
PA5183a,
PA5252a,
PA5440a,
PA0457.1,
pyoS5,
PA1021,
PA0123,
PA0891,
PA1020,
PA0440,
PA0007,
lptA,
PA0116,
PA0119,
PA1159,
PA0439,
codB,
PA0878,
PA2296,
PA0512,
PA0118,
codA,
PA1734,
PA0848,
PA1168,
cmpX,
PA0436,
PA0699,
PA0305,
PA0753,
PA0049,
PA1870,
PA0628,
PA1831,
PA0624,
PA0708,
PA0435,
PA0434,
flgB,
arsC,
PA5108,
PA5109,
PA0978,
PA0919,
PA5340,
PA5341
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员