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879357 mucA

879357

mucA

sigma factor AlgU negative regulator MucA

protein-coding

Pseudomonas aeruginosa PAO1

基因描述

Type Description
Definition sigma factor AlgU negative regulator MucA

研究结论

Date Results Publications
2020-06-20 11:37:00 The structures reveal the molecular basis for MucA recognition by MucB in the periplasm and AlgU in the cytoplasm, thus providing an important step in understanding the mechanisms that regulate a key signal transduction pathway involved in P. aeruginosa pathogenesis. 31297938
2018-12-22 10:09:00 mucA gene mutation influenced the virulence of Pseudomonas aeruginosa in P. aeruginosa pneumonia in COPD patients. 29957276
2017-05-27 11:55:00 AlgU controls rsmA transcription and is responsible for RsmA activity in mucA mutant strains. 27091153
2013-03-30 13:09:00 Inactivation of mucA (the gene responsible for the mucoid phenotype) in PAO1 leads to p38alpha MAPK activation by both TLR2 and TLR5, as observed in the cystic fibrosis clinical mucoid isolate PACF508. 23068105
2012-10-06 10:50:00 Alginate biosynthesis in Pseudomonas aeruginosa is a highly regulated by algU and mucA genes. 22842599

名称对应

Type IDs
Gene
UniProtKB-ID: MUCA_PSEAE
UniprotKB: P38107
UniParc: UPI000012F8D3
EMBL: AE004091, L14760, U49151
EnsemblGenome: PA0763
KO: pae:PA0763
Nucleutide sequences
EMBL-CDS: AAA87629.1, AAC43715.1, AAG04152.1
EnsemblGenome_TRS: AAG04152
Protein sequencees
EnsemblGenome_PRO: AAG04152
RefSeq: NP_249454.1
Others
UniRef100: UniRef100_P38107
UniRef90: UniRef90_P38107
UniRef50: UniRef50_P38107

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