| Type | Description |
|---|---|
| Definition | transcriptional regulator RhlR |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:15:00 | The interaction of RhlR-5'UTR with PhrD in E. coli indicated that this regulation could function without the involvement of any Pseudomonas specific proteins. | 30674910 |
| 2020-02-08 10:11:00 | Inactivation of RhlR protein (rhlR) of Pseudomonas aeruginosa does not block the quorum-sensing (QSR), nor impairs the virulence, and that even a LasR protein (lasR) rhlR double mutant presents residual virulence, even lacking the production of virulence factors. These results show that the inhibition of either lasR or rhlR is not a straightforward approach to blocking virulence, due to the great complexity of the QSR. | 30707095 |
| 2019-09-21 12:20:00 | Study identifies the mechanism of the binding of the autoinducer BHL ligand to the dimeric RhlR protein, which would further help the dimeric RhlR protein to bind the cognate promoter DNA to initiate the transcription of virulence genes. Also, the key amino acid residues from the RhlR protein were identified to be involved in ligand binding, protein-protein interactions, and DNA binding. | 29968257 |
| 2019-04-20 12:16:00 | rhlI mutants are unexpectedly more virulent than rhlR mutants, both in fly and in nematode intestinal infection models, suggesting that RhlR has RhlI-independent functions | 29523648 |
| 2018-10-20 10:38:00 | this work shows that PqsE and RhlR function as a QS-autoinducer synthase-receptor pair that drives group behaviors in P. aeruginosa. | 30224496 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RHLR_PSEAE
UniprotKB:
P54292
UniParc:
UPI000013387F
EMBL:
L28170,
AE004091,
U15644,
U40458,
L08962
EnsemblGenome:
PA3477
KO:
pae:PA3477
|
| Nucleutide sequences |
EMBL-CDS:
AAA62130.1,
AAC44036.1,
AAA25983.1,
AAA89073.1,
AAG06865.1
EnsemblGenome_TRS:
AAG06865
|
| Protein sequencees |
EnsemblGenome_PRO:
AAG06865
RefSeq:
NP_252167.1
|
| Others |
UniRef100:
UniRef100_P54292
UniRef90:
UniRef90_P54292
UniRef50:
UniRef50_P54292
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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