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878882 PA2018

878882

PA2018

multidrug efflux protein

protein-coding

Pseudomonas aeruginosa PAO1

基因描述

Type Description
Definition multidrug efflux protein

研究结论

Date Results Publications
2021-02-02 13:22:00 The Efflux Pump MexXY/OprM Contributes to the Tolerance and Acquired Resistance of Pseudomonas aeruginosa to Colistin. 31964794
2016-09-03 11:20:00 Polymyxin susceptibility in Pseudomonas aeruginosa is linked to the MexXY-OprM multidrug efflux system. 26369970
2016-03-26 10:27:00 The mechanism of development from sensitivity to resistance of P. aeruginosa to carbapenem during carbapenem treatment is due to porin oprD2 loss and an increased expression level of MexXY-OprM. 26125881
2015-04-15 13:00:00 The MexXY multidrug efflux pump was shown to enhance the effect of aminoglycoside modifying enzymes to develop high-level aminoglycoside resistance in Pseudomonas aeruginosa. 22282519
2014-11-08 11:51:00 Mutations of D133 and Y613 compromised aminoglycoside resistance, while, the K79 mutation enhanced aminoglycoside resistance, confirming a role for this putative proximal binding pocket in aminoglycoside recognition and export. 24757215

名称对应

Type IDs
Gene
UniProtKB-ID: G3XCW2_PSEAE, Q9RG59_PSEAI
UniprotKB: G3XCW2, Q9RG59
UniParc: UPI00000D420B
EMBL: AE004091, AF147719
EnsemblGenome: PA2018
KO: pae:PA2018
Nucleutide sequences
EMBL-CDS: AAG05406.1, AAF14523.1
Protein sequencees
RefSeq: NP_250708.1
Others
UniRef100: UniRef100_Q9RG59
UniRef90: UniRef90_Q9RG59
UniRef50: UniRef50_Q9RG59

全选

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研究热度

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