pilA - type 4 fimbrial protein PilA-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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878423 pilA

基因描述

Type	Description
Definition	type 4 fimbrial protein PilA

研究结论

Date	Results	Publications
2018-12-22 11:26:00	Glycosylation of type 4 fimbrial protein (PilA) protect Pseudomonas aeruginosa from certain pilus-specific phages. Alterations to PilA sequence can block phage infection, but glycosylation is less likely to create disadvantageous phenotypes. Through construction of chimeric phages, specific phage tail proteins allow infection of P. aeruginosa strains with glycosylated pili.	29133883
2016-12-24 11:13:00	PilS's phosphatase motif was required for the autoregulation of pilA transcription, suggesting that under conditions where PilA is abundant, the PilA-PilS interaction promotes PilR dephosphorylation and thus down-regulation of further pilA transcription.	27162347
2015-11-21 10:54:00	Data show that the type IV pilus (Tfp)-deficient mutant DeltapilA is severely attenuated in an acute pneumonia model of infection in the lungs of wild-type mice, but is virulent in the lungs of surfactant protein-A SP-A(-/-) mice.	24080545
2014-05-24 10:54:00	Found that the calcium-modulating cyclophilin ligand (CAMLG), which is involved in Ca(2+) signaling, was the major host cell PilA binding protein.	23266901
2013-06-29 10:18:00	PilA, the major pilin subunit, interacts with PilNOPQ. The results allow us to propose a model whereby PilA makes extensive contacts with the transenvelope complex, possibly to increase local concentrations of PilA monomers for polymerization.	23457250

名称对应

Type	IDs
Gene	UniProtKB-ID: PILA_PSEAE UniprotKB: P04739 UniParc: UPI000012AAC6 EMBL: M11323, AE004091 EnsemblGenome: PA4525 KO: pae:PA4525
Nucleutide sequences	EMBL-CDS: AAA25954.1, AAG07913.1 EnsemblGenome_TRS: AAG07913
Protein sequencees	EnsemblGenome_PRO: AAG07913 RefSeq: NP_253215.1
Others	UniRef100: UniRef100_P04739 UniRef90: UniRef90_P04739 UniRef50: UniRef50_P04739

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mRNA

Protein

UniprotKB

Description

Refseq

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Ensembl: {{protein.nucleotideEnsembl}}

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Ensembl: {{protein.proteinEnsembl}}

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Definition: {{{protein.definition}}}

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Location

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Pubmed编号	文献信息	发表日期	相关基因
29133883	Pseudomonas aeruginosa defends against phages through type IV pilus glycosylation. Nat Microbiol Hanjeong Harvey , Joseph Bondy-Denomy , HÃ©lÃ¨ne Marquis , Kristina M Sztanko , Alan R Davidson , Lori L Burrows	2018-01-01	-
27162347	Type IV pilins regulate their own expression via direct intramembrane interactions with the sensor kinase PilS. Proc. Natl. Acad. Sci. U.S.A. Sara L N Kilmury , Lori L Burrows	2016-05-24	-
24080545	Type IV pilus of Pseudomonas aeruginosa confers resistance to antimicrobial activities of the pulmonary surfactant protein-A. J Innate Immun Rommel Max Tan , Zhizhou Kuang , Yonghua Hao , Gee W Lau	2014-01-01	Sftpa1, pilA
23266901	Type IV pilus protein PilA of Pseudomonas aeruginosa modulates calcium signaling through binding the calcium-modulating cyclophilin ligand. J. Infect. Chemother. Jun Okuda , Naoki Hayashi , Munenori Arakawa , Shu Minagawa , Naomasa Gotoh	2013-08-01	-
23457250	PilMNOPQ from the Pseudomonas aeruginosa type IV pilus system form a transenvelope protein interaction network that interacts with PilA. J. Bacteriol. Stephanie Tammam , Liliana M Sampaleanu , Jason Koo , Kumararaaj Manoharan , Mark Daubaras , Lori L Burrows , P Lynne Howell	2013-05-01	pilA, pilQ, pilP, pilO, pilN, pilM
18978025	Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Nucleic Acids Res. Geoffrey L Winsor , Thea Van Rossum , Raymond Lo , Bhavjinder Khaira , Matthew D Whiteside , Robert E W Hancock , Fiona S L Brinkman	2009-01-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
17015649	Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. J. Bacteriol. Ryan T Cirz , Bryan M O'Neill , Jennifer A Hammond , Steven R Head , Floyd E Romesberg	2006-10-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
16030221	Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. J. Bacteriol. Kelli L Palmer , Lauren M Mashburn , Pradeep K Singh , Marvin Whiteley	2005-08-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
15995206	A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. J. Bacteriol. Prabhakar Salunkhe , Catherine H M Smart , J Alun W Morgan , Stavroula Panagea , Martin J Walshaw , C Anthony Hart , Robert Geffers , Burkhard TÃ¼mmler , Craig Winstanley	2005-07-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341
15908409	Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Infect. Immun. M J Filiatrault , V E Wagner , D Bushnell , C G Haidaris , B H Iglewski , L Passador	2005-06-01	PA2755a, PA4636a, PA0032a, PA0041a, PA0103a, PA0306a, PA0367a, PA0451a, PA0701a, PA0736a, PA0788a, PA0951a, PA1019a, PA1052a, PA1112a, PA1112b, PA1424a, PA1428a, PA1483a, PA1578a, PA1643a, PA1797a, PA1833a, PA1837a, PA1866a, PA2118a, PA2142a, PA2173a, PA2312a, PA2559a, PA2746a, PA2747a, PA2750a, PA2754a, PA2763a, PA2772a, PA3089a, PA3303a, PA3403a, PA3440a, PA3574a, PA3733a, PA3865a, PA3886a, PA3963a, PA3969a, PA4027a, PA4108a, PA4145a, PA4313a, PA4360a, PA4635a, PA4690a, PA5183a, PA5252a, PA5440a, PA0457.1, pyoS5, PA1021, PA0123, PA0891, PA1020, PA0440, PA0007, lptA, PA0116, PA0119, PA1159, PA0439, codB, PA0878, PA2296, PA0512, PA0118, codA, PA1734, PA0848, PA1168, cmpX, PA0436, PA0699, PA0305, PA0753, PA0049, PA1870, PA0628, PA1831, PA0624, PA0708, PA0435, PA0434, flgB, arsC, PA5108, PA5109, PA0978, PA0919, PA5340, PA5341

研究热度

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