| Type | Description |
|---|---|
| Definition | RNA-binding protein Hfq |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:15:00 | Hfq and sRNA 179 Inhibit Expression of the Pseudomonas aeruginosa cAMP-Vfr and Type III Secretion Regulons. | 32546612 |
| 2020-06-13 11:40:00 | Results have found that Hfq is critical for the growth of P. aeruginosa strain PAO1. The reduced growth observed in hfq mutants was due, at least in part, to the activities of genes whose expression is positively regulated by MexT. | 31358608 |
| 2020-04-04 10:43:00 | We describe high-resolution cryo-EM structures of the assembly of Hfq and Crc bound to the translation initiation site of a target mRNA. The core of the assembly is formed through interactions of two cognate RNAs, two Hfq hexamers and a Crc pair. | 30758287 |
| 2019-10-05 11:49:00 | findings indicate that Hfq binds many transcripts co-transcriptionally in P. aeruginosa, often in concert with Crc, and uncover direct regulatory targets of these proteins. | 29719264 |
| 2019-07-06 12:42:00 | It has been shown that Crc and Hfq form an assembly in the presence of RNAs containing A-rich motifs, and that Crc interacts with both, Hfq and RNA. Through these interactions, Crc enhances the stability of Hfq/Crc/RNA complexes, which can explain its facilitating role in Hfq-mediated translational repression. | 29244160 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HFQ_PSEAE
UniprotKB:
Q9HUM0
UniParc:
UPI000012C6A3
EMBL:
AE004091
EnsemblGenome:
PA4944
KO:
pae:PA4944
|
| Nucleutide sequences |
EMBL-CDS:
AAG08329.1
EnsemblGenome_TRS:
AAG08329
|
| Protein sequencees |
EnsemblGenome_PRO:
AAG08329
RefSeq:
NP_253631.1
|
| Others |
UniRef100:
UniRef100_A6VD57
UniRef90:
UniRef90_A6VD57
UniRef50:
UniRef50_A6VD57
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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