| Type | Description |
|---|---|
| Definition | RIO kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-27 11:05:00 | RIO kinase 3 (RIOK3) positively regulates the activity of the AKT/mTOR pathway in glioma cells. | 29233656 |
| 2016-01-16 11:39:00 | the ectopic expression of RIOK3 or a phosphomimetic MDA5-S828D mutation attenuated MDA5-mediated signaling. | 25865883 |
| 2015-11-28 10:09:00 | These findings demonstrate that RIOK3 is necessary for maintaining actin cytoskeletal organisation required for migration and invasion, biological processes that are necessary for hypoxia-driven metastasis. | 25486436 |
| 2014-12-06 12:15:00 | Functionally, RIOK3 acts as a SUFU-dependent positive regulator of Hedgehog signaling. | 24018050 |
| 2014-08-23 11:15:00 | Authors found that RIOK3 physically interacts with TBK1 and IRF3 and bridges the functions between TBK1 and IRF3 in the activation of type I interferon pathway. | 24807708 |
| Type | IDs |
|---|---|
| Synonymous | SUDD |
| Gene |
UniProtKB-ID:
RIOK3_HUMAN,
B0YJ89_HUMAN,
B4E1Q4_HUMAN
UniprotKB:
O14730,
B0YJ89,
B4E1Q4
UniParc:
UPI000007436D,
UPI00017A873F,
UPI000013C732
EMBL:
AK057292,
BC039729,
HM005587,
AF013591,
CH471088,
AK303938,
EF445025,
AC026634
Ensembl:
ENSG00000101782
KO:
hsa:8780
|
| Nucleutide sequences |
EMBL-CDS:
AAC26080.1,
AAH39729.1,
BAG51898.1,
AEE61184.1,
EAX01151.1,
ACA06067.1,
BAG64866.1
Gene_ORFName:
hCG_37755
Ensembl_TRS:
ENST00000577501,
ENST00000339486,
ENST00000581585
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000462548,
ENSP00000341874,
ENSP00000463660
RefSeq:
XP_011524545.1,
NP_003822.2,
NP_001335122.1,
XP_011524544.1
|
| Others |
UniRef100:
UniRef100_B4E1Q4,
UniRef100_O14730
UniRef90:
UniRef90_O14730
UniRef50:
UniRef50_O14730
UniGene:
Hs.445511,
Hs.728452
CCDS:
CCDS11877.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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