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8778 SIGLEC5

8778

SIGLEC5

sialic acid binding Ig like lectin 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition sialic acid binding Ig like lectin 5

研究结论

Date Results Publications
2020-09-12 15:57:00 Genetic susceptibility of common polymorphisms in NIN and SIGLEC5 to chronic periodontitis. 30765789
2020-07-18 11:58:00 Soluble siglec-5 is a novel salivary biomarker for primary Sjogren's syndrome. 30922727
2019-06-22 12:06:00 Plasma Siglec-5 levels are implicated as an early diagnostic marker of CLI in T2DM patients and it may become a target for the prevention or treatment of CLI in diabetes. 28900239
2018-07-14 10:10:00 PSGL1 and Siglec-5 are in close proximity at the leukocyte surface.SPSGL1 is a ligand for Siglec-5 and interacts with Siglec-5 ectodomain.Siglec-5 plays a role in PSGL1-mediated leukocyte rolling and the inflammatory response in general. 27892504
2016-02-27 11:14:00 An unbiased screen revealed Hsp70 as a ligand for Siglec-5 and Siglec-14. Hsp70 stimulation through Siglec-5 delivers an anti-inflammatory signal, while stimulation through Siglec-14 is pro-inflammatory. 26459514

名称对应

Type IDs
Synonymous CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5
Gene
UniProtKB-ID: SIGL5_HUMAN
UniprotKB: O15389
UniParc: UPI000011B40C
EMBL: AF170484, AC018755, U71383, BC029896
Ensembl: ENSG00000105501
KO: hsa:8778
Nucleutide sequences
EMBL-CDS: AAD50978.1, AAB70703.1, AAH29896.1, AAF87846.1
Ensembl_TRS: ENST00000534261
Protein sequencees
Ensembl_PRO: ENSP00000473238
RefSeq: NP_001371638.1, NP_001371637.1, XP_016882908.1, NP_003821.1
Others
UniRef100: UniRef100_O15389
UniRef90: UniRef90_O15389
UniRef50: UniRef50_O15389
UniGene: Hs.310333
CCDS: CCDS33088.1

全选

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