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8766 RAB11A

8766

RAB11A

RAB11A, member RAS oncogene family

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAB11A, member RAS oncogene family

研究结论

Date Results Publications
2020-07-25 10:13:00 In vitro reconstitution revealed that the membrane is necessary for the formation of ACBD3:PI4KB:Rab11 protein complex at physiological (nanomolar) concentrations. 30679637
2020-07-11 12:26:00 Rab11a has a role in the trafficking of alphaVbeta3 integrin and maintenance of E-cadherin levels at the surface of endometrial epithelial cells 30597006
2020-06-20 10:06:00 Reduced levels of Rab11a expression is linked to both advanced-stage carcinoma and poorer survival rates in the colorectal cancer. 31239271
2020-06-13 10:26:00 Expression of wild-type Rab11a in Rab11a knockout cells rescued the late endosome/lysosome phenotype. Overall, these results indicate that Rab11a and Rab11b have overlapping and distinct functions and that Rab11a, unexpectedly, plays a central role in the homeostasis of endosomal-lysosomal biogenesis. 30981667
2020-05-30 10:21:00 These findings demonstrate a complex regulation/perturbation pattern of signaling cascades involving MAPK/AKT/RAB11 in spinal cord tissue from Amyotrophic lateral sclerosis patients. 31196199

名称对应

Type IDs
Synonymous YL8
Gene
UniProtKB-ID: RB11A_HUMAN, A0A024R5Z8_HUMAN
UniprotKB: P62491, A0A024R5Z8
UniParc: UPI00017A7AA5, UPI0000029ED1
EMBL: CR536493, AK311770, BT020154, X56740, AC011939, CH471082, AC084854, BC013348, AK300008, CR407669, BT020151, X53143, AF498946, AF000231
Ensembl: ENSG00000103769
KO: hsa:8766
Nucleutide sequences
EMBL-CDS: BAG34713.1, AAM21094.1, CAG38732.1, AAV38956.1, AAH13348.1, BAG61825.1, CAA37300.1, CAG28597.1, AAV38953.1, AAC32887.1, CAA40064.1, EAW77752.1, EAW77753.1
Gene_ORFName: hCG_22519
Ensembl_TRS: ENST00000261890, ENST00000569896
Protein sequencees
Ensembl_PRO: ENSP00000261890, ENSP00000456420
RefSeq: NP_004654.1, NP_001193765.1
Others
UniRef100: UniRef100_P62491
UniRef90: UniRef90_P62491
UniRef50: UniRef50_P62491
UniGene: Hs.321541
CCDS: CCDS10212.1, CCDS58373.1

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