| Type | Description |
|---|---|
| Definition | ADAM metallopeptidase domain 15 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:15:00 | ADAM15 mediates upregulation of Claudin-1 expression in breast cancer cells. | 31467400 |
| 2020-10-10 13:00:00 | ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm. | 32522006 |
| 2020-06-27 12:15:00 | The absence of ADAM15 at low shear stress or static conditions may therefore lead to increased endothelial damage. | 31271758 |
| 2019-12-14 10:52:00 | The data show that ADAM15 plays a role in rheumatoid arthritis angiogenesis, suggesting that ADAM15 might be a potential target in inflammatory diseases such as rheumatoid arthritis. | 30634456 |
| 2019-11-02 13:28:00 | The antiapoptotic effect of ADAM15 in FasL-stimulated cells was demonstrated either by increased apoptosis of cells transfected with an ADAM15 construct lacking the cytoplasmic domain compared to cells transfected with full-length ADAM15 or by reduced apoptosis resistance of rheumatoid arthritis synovial fibroblasts upon RNA interference silencing of ADAM15. | 30003689 |
| Type | IDs |
|---|---|
| Synonymous | MDC15 |
| Gene |
UniProtKB-ID:
ADA15_HUMAN
UniprotKB:
Q13444
UniParc:
UPI000035CC78,
UPI0001D896DE,
UPI0001D896DF,
UPI000035CC75,
UPI0000D61FFE,
UPI0001AE7904,
UPI000035CC76,
UPI0000237C77,
UPI00004700D4,
UPI0001D896DD,
UPI000035CC77,
UPI00001AE986,
UPI0001F78807
EMBL:
AK297468,
AY560596,
BC014566,
AY560599,
AY576417,
AY560593,
AY560598,
AY560595,
AK296925,
AY560601,
AY518542,
BT009764,
AY560600,
AL691442,
U46005,
AL451085,
AF314227,
AY560594,
AY560597,
U41767,
AK075498
Ensembl:
ENSG00000143537
KO:
hsa:8751
|
| Nucleutide sequences |
EMBL-CDS:
AAP88766.1,
AAC50404.1,
AAS72997.1,
AAS48594.1,
AAS72991.1,
AAS72998.1,
AAS72995.1,
AAC51112.1,
BAG59477.1,
AAS48597.1,
AAR99331.1,
AAS72994.1,
AAS72999.1,
BAG52157.1,
AAS72298.1,
BAG59890.1,
AAS48595.1,
AAS48591.1,
AAS48592.1,
AAS48596.1,
AAS72996.1,
AAS72992.1,
AAS48590.1,
AAM44189.1,
AAS73000.1,
AAH14566.1,
AAS72993.1,
AAS48593.1
Ensembl_TRS:
ENST00000359280,
ENST00000355956,
ENST00000447332,
ENST00000360674,
ENST00000529473,
ENST00000449910,
ENST00000271836,
ENST00000368412,
ENST00000356955,
ENST00000526491,
ENST00000368413,
ENST00000531455
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000403843,
ENSP00000353892,
ENSP00000357398,
ENSP00000352226,
ENSP00000432927,
ENSP00000476000,
ENSP00000357397,
ENSP00000271836,
ENSP00000434227,
ENSP00000349436,
ENSP00000432347,
ENSP00000348227
RefSeq:
NP_997077.1,
NP_001248395.1,
NP_997078.1,
NP_997074.1,
NP_001248393.1,
NP_003806.3,
NP_997080.1,
NP_001248394.1,
NP_997079.1
|
| Others |
UniRef100:
UniRef100_Q13444
UniRef90:
UniRef90_Q13444
UniRef50:
UniRef50_Q13444
UniGene:
Hs.312098
CCDS:
CCDS60282.1,
CCDS58032.1,
CCDS44236.1,
CCDS58031.1,
CCDS1085.1,
CCDS1088.1,
CCDS1086.1,
CCDS1084.1,
CCDS1087.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.proteinEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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