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8747 ADAM21

8747

ADAM21

ADAM metallopeptidase domain 21

protein-coding

Homo sapiens

基因描述

Type Description
Definition ADAM metallopeptidase domain 21

研究结论

Date Results Publications
2019-07-27 10:58:00 ADAM21 was overexpressed in KYN-2 hepatocellular carcinoma (HCC) cell line, and its knockdown reduced invasion, migration, proliferation, and metastasis relative to controls. In HCC clinical specimens, ADAM21 positivity was associated with vascular invasion, large tumor size, high histological grade, and lower overall and recurrence-free survival as compared to cases that were negative for ADAM21 expression. 29138461

名称对应

Type IDs
Synonymous ADAM 21, ADAM31
Gene
UniProtKB-ID: ADA21_HUMAN
UniprotKB: Q9UKJ8
UniParc: UPI000013D756
EMBL: AF029900, AL391223, BC109024, AL357153, BC109025, AF158644
Ensembl: ENSG00000139985
KO: hsa:8747
Nucleutide sequences
EMBL-CDS: AAC52042.1, AAI09026.1, AAD55255.1, AAI09025.1
Ensembl_TRS: ENST00000603540
Protein sequencees
Ensembl_PRO: ENSP00000474385
RefSeq: NP_003804.2
Others
UniRef100: UniRef100_Q9UKJ8
UniRef90: UniRef90_Q9UKJ8
UniRef50: UniRef50_Q9UKJ8
UniGene: Hs.178748
CCDS: CCDS9804.1

全选

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