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8745 ADAM23

8745

ADAM23

ADAM metallopeptidase domain 23

protein-coding

Homo sapiens

基因描述

Type Description
Definition ADAM metallopeptidase domain 23

研究结论

Date Results Publications
2019-05-18 11:18:00 Results indicate that ADAM23 is likely involved in breast cancer (BC) progression and dissemination of mesenchymal circulating tumor cells. ADAM23 methylation has the potential to function as a novel prognostic marker. 30815959
2018-12-22 12:33:00 The relationships between the decreased methylation levels of the SNAI2 and ADAM23 genes and cancer de-differentiation and haematogenous dissemination, respectively, indicate novel functions of those genes in the invasive processes. 30189837
2018-11-10 11:57:00 Our results demonstrate that ADAM23 expression is likely involved in the progression of epithelial ovarian cancer 29921495
2017-11-04 10:39:00 ADAM23 regulates neuronal differentiation by triggering specific signaling pathways during human neural progenitor cells differentiation. 28828010
2017-05-13 11:55:00 these results support the existence of a second mechanism, alternative to inhibition of protein secretion, by which ADLTE-causing LGI1 mutations exert their loss-of-function effect extracellularly, and suggest that interactions of LGI1 with both ADAM22 and ADAM23 play an important role in the molecular mechanisms leading to utosomal dominant lateral temporal epilepsy 27760137

名称对应

Type IDs
Synonymous MDC-3, MDC3
Gene
UniProtKB-ID: ADA23_HUMAN, E7EWD3_HUMAN, A0A024R3W8_HUMAN
UniprotKB: O75077, E7EWD3, A0A024R3W8
UniParc: UPI0000470EB0, UPI0000470EB1, UPI0000044543, UPI000204A86F
EMBL: CH471063, AC009225, BC132763, BC132765, AC010731, AC079136, AB009672, AJ005580
Ensembl: ENSG00000114948
KO: hsa:8745
Nucleutide sequences
EMBL-CDS: BAA32351.1, CAC20565.1, AAI32766.1, AAI32764.1, EAW70386.1, EAW70387.1
Gene_ORFName: hCG_1811623
Ensembl_TRS: ENST00000264377, ENST00000374415
Protein sequencees
Ensembl_PRO: ENSP00000264377, ENSP00000363536
RefSeq: XP_011510388.1, XP_005246989.1, NP_003803.1
Others
UniRef100: UniRef100_E7EWD3, UniRef100_O75077
UniRef90: UniRef90_O75077
UniRef50: UniRef50_O75077
UniGene: Hs.370287, Hs.591643
CCDS: CCDS2369.1

全选

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