| Type | Description |
|---|---|
| Definition | glycosylphosphatidylinositol anchor attachment 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:29:00 | GPAA1 promotes progression of childhood acute lymphoblastic leukemia through regulating c-myc. | 32432756 |
| 2020-10-31 13:17:00 | A novel variant in GPAA1, encoding a GPI transamidase complex protein, causes inherited vascular anomalies with various phenotypes. | 32533362 |
| 2019-12-21 10:15:00 | Mechanistically, GPAA1 enhanced the levels of metastasis-associated GPI-anchored proteins to increase tumour metastasis and intensified lipid raft formation, which consequently promoted the interaction between EGFR and ERBB2 as well as downstream pro-proliferative signalling. | 31118109 |
| 2017-11-18 10:56:00 | The splicing mutation was found to decrease GPAA1 mRNA. | 29100095 |
| 2015-01-24 12:41:00 | the lumenal domain of GAA1/GPAA1 has a 3D structure similar to that of an M28-type aminopeptidase. GAA1/GPAA1 is a candidate for the enzyme that catalyzes the peptide bond formation between the omega-site and a phosphoethanolamine group of GPI lipid anchor. | 24743167 |
| Type | IDs |
|---|---|
| Synonymous | GAA1, GPIBD15, hGAA1 |
| Gene |
UniProtKB-ID:
GPAA1_HUMAN
UniprotKB:
O43292
UniParc:
UPI0000073ECC,
UPI00001BD951
EMBL:
BC004129,
BC006383,
AB002137,
AL157437,
AB017267,
AB002135,
BC003171,
AB006969
Ensembl:
ENSG00000197858
KO:
hsa:8733
|
| Nucleutide sequences |
EMBL-CDS:
BAA24035.1,
AAH03171.1,
BAA82590.1,
BAA82587.1,
AAH04129.1,
BAA82588.1,
AAH06383.2,
CAB75660.2
Ensembl_TRS:
ENST00000355091,
ENST00000361036
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347206,
ENSP00000354316
RefSeq:
NP_003792.1
|
| Others |
UniRef100:
UniRef100_O43292
UniRef90:
UniRef90_O43292
UniRef50:
UniRef50_O43292
UniGene:
Hs.627962
CCDS:
CCDS43776.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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