| Type | Description |
|---|---|
| Definition | RNA guanylyltransferase and 5'-phosphatase |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 11:39:00 | c-Myc deregulation induces mRNA capping enzyme dependency in tumor cells. | 27756891 |
| 2015-04-11 13:35:00 | These results identify a new domain of CE that is specific to its function in cytoplasmic capping, and a new role for Nck1 in regulating gene expression through its role as the scaffold for assembly of the cytoplasmic capping complex. | 25137142 |
| 2013-07-20 11:23:00 | Our biochemical studies provide the first insight that MZP can inhibit the formation of the RNA cap structure catalyzed by HCE. | 23349942 |
| 2011-10-01 12:07:00 | Data show that human capping enzyme residues 229-567 comprise the minimum enzymatically active human GTase (hGTase) domain and determine the structure by X-ray crystallography. | 21636784 |
| 2010-06-30 22:06:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | CAP1A, HCE, HCE1, hCAP |
| Gene |
UniProtKB-ID:
MCE1_HUMAN,
B4DSJ8_HUMAN,
Q7Z3R6_HUMAN
UniprotKB:
O60942,
B4DSJ8,
Q7Z3R6
UniParc:
UPI000002ADB9,
UPI00017A7B28,
UPI000002ADB8,
UPI00001A9962,
UPI000012ED6E,
UPI000002ADBA
EMBL:
AB012142,
AB009024,
AL096868,
AB012143,
AK299777,
AL079342,
BC019954,
AL133408,
AB009023,
CH471051,
BX537450,
AB009022,
AL445530,
AF025654
Ensembl:
ENSG00000111880
KO:
hsa:8732
|
| Nucleutide sequences |
EMBL-CDS:
BAA25895.1,
EAW48569.1,
BAA25199.1,
BAA25894.1,
AAB91559.1,
EAW48566.1,
BAA25198.1,
EAW48570.1,
EAW48567.1,
BAA25896.1,
AAH19954.1,
BAG61660.1,
CAD97693.1
Ensembl_TRS:
ENST00000369475,
ENST00000538899,
ENST00000369485
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358487,
ENSP00000358497,
ENSP00000442609
RefSeq:
NP_001273355.1,
NP_001273357.1,
XP_016866891.1,
NP_003791.3,
XP_016866890.1
|
| Others |
UniRef100:
UniRef100_B4DSJ8,
UniRef100_O60942,
UniRef100_Q7Z3R6
UniRef90:
UniRef90_A0A2K6SSB7,
UniRef90_O60942
UniRef50:
UniRef50_O60942
UniGene:
Hs.567378
CCDS:
CCDS69153.1,
CCDS5017.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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