| Type | Description |
|---|---|
| Definition | RNA guanine-7 methyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 10:44:00 | Data show that most of the cell lines which exhibited enhanced dependency on RNA guanine-7 methyltransferase (RNMT) harboured oncogenic mutations in phosphatidylinositol 3-kinase catalytic 110-KD alpha (PI3Kalpha). | 30991934 |
| 2019-12-07 10:48:00 | Mechanism of allosteric activation of human RNMT by RAM has been reported. | 31329932 |
| 2019-10-05 11:49:00 | These findings suggest that multiple interactions among RNMT-RAM, RNA Pol II factors, and RNA along the transcription unit stimulate transcription. | 29719263 |
| 2017-11-11 13:09:00 | Results identify a cytoplasmic pool of RNMT which is a component of the cytoplasmic capping complex, and demonstrate its function as the methyltransferase that catalyzes the final maturation step in cap homeostasis. | 28981715 |
| 2017-10-21 10:31:00 | MYC promotes mRNA cap methylation and protein production of Wnt/beta-catenin signaling transcripts through recruitment of cyclin-dependent kinase 7 (CDK7) and consequently RNMT to gene promoters. | 27899423 |
| Type | IDs |
|---|---|
| Synonymous | CMT1, CMT1c, MET, Met, RG7MT1, cm1p, hCMT1, hMet |
| Gene |
UniProtKB-ID:
MCES_HUMAN,
A8K946_HUMAN
UniprotKB:
O43148,
A8K946
UniParc:
UPI000006F958,
UPI00015DA90F,
UPI00000705F3
EMBL:
AB020966,
CH471113,
AK292561,
AB022604,
EF445026,
AB007858,
BC036798,
AB022605,
AF067791
Ensembl:
ENSG00000101654
KO:
hsa:8731
|
| Nucleutide sequences |
EMBL-CDS:
EAX01506.1,
BAA23694.1,
EAX01505.1,
ACA06068.1,
AAH36798.1,
AAC63269.1,
BAA74463.1,
BAA82447.1,
BAA74464.1,
BAF85250.1
Ensembl_TRS:
ENST00000592764,
ENST00000543302,
ENST00000589866,
ENST00000262173,
ENST00000383314
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262173,
ENSP00000446426,
ENSP00000372804,
ENSP00000466111,
ENSP00000466252
RefSeq:
NP_001295192.1,
NP_001365061.1,
XP_011524053.1,
XP_011524051.1,
NP_001365063.1,
XP_011524055.1,
NP_003790.1,
NP_001365064.1,
XP_011524052.1
|
| Others |
UniRef100:
UniRef100_A8K946,
UniRef100_O43148
UniRef90:
UniRef90_O43148
UniRef50:
UniRef50_O43148
UniGene:
Hs.592347
CCDS:
CCDS11867.1,
CCDS77156.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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