| Type | Description |
|---|---|
| Definition | carbonyl reductase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:27:00 | Dehydrogenase/reductase activity of human carbonyl reductase 1 with NADP(H) acting as a prosthetic group. | 31759632 |
| 2019-05-25 12:08:00 | These findings suggest that CBR1 generating 20beta-dihydrocortisol is a novel pathway modulating GR activation and providing enzymatic protection against excessive GR activation in obesity. | 28878267 |
| 2019-01-12 11:19:00 | Findings suggest that CBR1 has an important role in DNA damage response through regulation of irradiation-mediated generation causing to regulation of radiosensitivity, and CBR1 inhibition with IR might be a potent therapeutic strategy for head and neck squamous cell carcinoma treatment. | 30376862 |
| 2018-11-03 10:05:00 | This study examined the impact of the functional single nucleotide polymorphism CBR1 rs9024 on the bioactivation of loxoprofen in a collection of human liver samples and tumor cell lines. | 29851133 |
| 2018-01-06 12:29:00 | CRB1 is an efficient catalyst for the reduction of glutathionylated aldehydes derived from lipid peroxidation. | 27562619 |
| Type | IDs |
|---|---|
| Synonymous | CBR, SDR21C1, hCBR1 |
| Gene |
UniProtKB-ID:
CBR1_HUMAN,
A0A384NL53_HUMAN
UniprotKB:
P16152,
A0A384NL53
UniParc:
UPI000004C784,
UPI0000EE4C8D
EMBL:
AK294142,
EF141836,
AK314879,
BC015640,
GQ900926,
CH471079,
AP001724,
AB124848,
CR541708,
BT019843,
BC002511,
J04056,
AB003151,
AP000688,
M62420
Ensembl:
ENSG00000159228
KO:
hsa:873
|
| Nucleutide sequences |
EMBL-CDS:
AAV38646.1,
BAA33498.1,
AAA52070.1,
CAG46509.1,
ABK97430.1,
BAG37394.1,
AAH15640.1,
BAA95508.1,
AAH02511.1,
AAA17881.1,
BAE45940.1,
EAX09754.1,
BAA89424.1,
EAX09755.1,
BAG57468.1,
ADO22443.1
Ensembl_TRS:
ENST00000290349,
ENST00000530908
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000434613,
ENSP00000290349
RefSeq:
NP_001273718.1,
NP_001748.1
|
| Others |
UniRef100:
UniRef100_P16152
UniRef90:
UniRef90_P16152
UniRef50:
UniRef50_P16152
UniGene:
Hs.88778
CCDS:
CCDS13641.1,
CCDS68202.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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