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8726 EED

8726

EED

embryonic ectoderm development

protein-coding

Homo sapiens

基因描述

Type Description
Definition embryonic ectoderm development

研究结论

Date Results Publications
2020-09-26 13:05:00 PICOT binding to chromatin-associated EED negatively regulates cyclin D2 expression by increasing H3K27me3 at the CCND2 gene promoter. 31527584
2020-05-30 11:59:00 BR-001, a potent inhibitor of the EED subunit of the PRC2 complex, suppresses tumor progression by modulating the tumor microenvironment. 31395608
2020-05-09 13:14:00 review the PRC2 complex and clinical syndromes of overgrowth and intellectual disability associated with core components EZH2, EED, and SUZ12 31724824
2020-05-02 10:23:00 Identification of mutations in the PRC2 components EED and SUZ12 in the majority of MPNSTs may imply noncanonical oncogenic activities of the intact component, EZH2, and provide new opportunities for therapeutic intervention. 31023785
2020-04-25 11:54:00 Mutation in the EED gene is associated with Cohen-Gibson syndrome. 30793471

名称对应

Type IDs
Synonymous COGIS, HEED, WAIT1
Gene
UniProtKB-ID: EED_HUMAN, E9PJK2_HUMAN
UniprotKB: O75530, E9PJK2
UniParc: UPI00003534F9, UPI00005A3EC4, UPI00000E88CF, UPI0000141B89
EMBL: AF078933, BC068995, AP003084, CH471076, AF070418, AF099032, AF080227, U90651, AK292120, BC047672
Ensembl: ENSG00000074266
KO: hsa:8726
Nucleutide sequences
EMBL-CDS: AAC23685.1, AAC68675.1, EAW75129.1, EAW75130.1, BAF84809.1, AAD08714.1, AAC95144.1, AAH68995.1, AAH47672.1, AAD08815.1
Ensembl_TRS: ENST00000263360, ENST00000351625, ENST00000672825, ENST00000327320, ENST00000528180
Protein sequencees
Ensembl_PRO: ENSP00000315587, ENSP00000500834, ENSP00000263360, ENSP00000338186, ENSP00000431778
RefSeq: XP_016874002.1, XP_016874001.1, XP_011543632.1, NP_003788.2, NP_001317263.1, NP_001294936.1, XP_011543633.1
Others
UniRef100: UniRef100_O75530, UniRef100_E9PJK2
UniRef90: UniRef90_O75530, UniRef90_E9PJK2
UniRef50: UniRef50_A0A452VHG0, UniRef50_O75530
UniGene: Hs.503510
CCDS: CCDS8273.1, CCDS76463.1

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