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8725 URI1

8725

URI1

URI1 prefoldin like chaperone

protein-coding

Homo sapiens

基因描述

Type Description
Definition URI1 prefoldin like chaperone

研究结论

Date Results Publications
2020-04-11 12:42:00 HBx and c-MYC are involved in URI1 expression in HCC-B. URI1 expression may play important roles in the development and progression of HCC-B because HBx and c-MYC are well-known oncogenic factors in the virus and host 31739577
2018-04-07 11:32:00 Collectively, these findings indicate that RMP promotes Epithelial-mesenchymal transition and hepatocellular carcinoma metastasis through NF-kappaB/CSN2/Snail pathway. These results suggest that RMP and p65 may serve as potential candidates of the targets in the treatment of metastatic hepatocellular carcinoma. 28423737
2018-01-13 13:52:00 These findings suggest that URI1 has properties of a 'non-oncogene' that supports the oncogenic phenotype of those cancer cells that have evolved a dependency on this molecular chaperone system for survival 27105489
2017-08-26 12:20:00 This work uncovers that URI-regulated OGT confers c-MYC-dependent survival functions in response to glucose fluctuations. 27505673
2017-08-19 10:20:00 Amplification of 19q12 CCNE1/URI was found in 10.4% (28/270) and was significantly associated with type II endometrial cancer (EC) high grade, advanced FIGO stage, and aberrant tumor supressor p53 expression. 27582547

名称对应

Type IDs
Synonymous C19orf2, NNX3, PPP1R19, RMP, URI
Gene
UniProtKB-ID: RMP_HUMAN
UniprotKB: O94763
UniParc: UPI00001604C8, UPI00024B9D23, UPI0001A51BA2, UPI000013F767
EMBL: BC026184, AF091095, AB006572, AK292170, AC008507
Ensembl: ENSG00000105176
KO: hsa:8725
Nucleutide sequences
EMBL-CDS: AAD08679.1, AAH26184.2, BAF84859.1, BAA34781.1
Ensembl_TRS: ENST00000392271, ENST00000360605
Protein sequencees
Ensembl_PRO: ENSP00000376097, ENSP00000353817
RefSeq: XP_005259419.1, XP_024307519.1, NP_003787.2, XP_005259420.1, XP_011525737.1, NP_001239570.1
Others
UniRef100: UniRef100_O94763
UniRef90: UniRef90_O94763
UniRef50: UniRef50_O94763
UniGene: Hs.466391
CCDS: CCDS58658.1, CCDS12420.1

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