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8723 SNX4

8723

SNX4

sorting nexin 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition sorting nexin 4

研究结论

Date Results Publications
2017-10-21 12:46:00 Results indicate that SNX4-mediated regulation of the steady-state levels and trafficking of BACE1, as well as the subsequent increase in BACE1-mediated cleavage, may be relevant to Alzheimer's disease progression. 28109317
2015-12-19 10:14:00 alpha-taxilin interacts with SNX4 and plays a role in the recycling pathway of TfnR. 24690921
2012-06-16 12:30:00 SNX4, but not SNX1 and SNX8, is associated with the Rab11-recycling endosomes and that a high frequency of SNX4-mediated tubule formation is observed as endosomes undergo Rab4-to-Rab11 transition. 21973056
2010-06-30 22:06:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614
2010-01-21 00:00:00 by driving membrane tubulation, SNX4 coordinates iterative, geometric-based sorting of the TfnR with the long-range transport of carriers from early endosomes to the ERC 17994011

名称对应

Type IDs
Synonymous ATG24B
Gene
UniProtKB-ID: SNX4_HUMAN
UniprotKB: O95219
UniParc: UPI00017A7BCC, UPI000003586D
EMBL: AF065485, CH471052, AC117487, AK298972, BC018762, AC080096, AK001835
Ensembl: ENSG00000114520
KO: hsa:8723
Nucleutide sequences
EMBL-CDS: EAW79390.1, AAC83149.1, BAG61066.1, EAW79393.1, BAG50982.1, AAH18762.1, EAW79391.1
Ensembl_TRS: ENST00000251775
Protein sequencees
Ensembl_PRO: ENSP00000251775
RefSeq: NP_003785.1, XP_016862903.1
Others
UniRef100: UniRef100_O95219
UniRef90: UniRef90_O95219
UniRef50: UniRef50_O95219
UniGene: Hs.507243
CCDS: CCDS3032.1

全选

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研究热度

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