| Type | Description |
|---|---|
| Definition | TNF receptor superfamily member 25 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses. | 33177161 |
| 2021-02-20 13:32:00 | The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens. | 32397343 |
| 2020-10-24 13:54:00 | Pathologic up-regulation of TNFSF15-TNFRSF25 axis sustains endothelial dysfunction in unprovoked venous thromboembolism. | 31135876 |
| 2020-05-30 13:50:00 | The identifies a new inflammatory mechanism in Mucosal-associated invariant T cells linking the DR3/TL1A axis with amplification of TCR-dependent and -independent effector functions, particularly inducing excessive innate TNF-alpha production. | 31628153 |
| 2020-01-04 12:03:00 | In contrast to pre-menopausal females, post-menopausal serum levels of TL1A are not significantly elevated and that DR3 expression is not induced on CD14+ monocytes. Murine ovariectomy (OVX) model of estrogen-deficiency revealed that early post-OVX expression of DR3 on CD4+ T cells is significantly elevated suggesting that DR3 and TL1A could play a potentially indirect role in early post-menopausal bone loss. | 31299941 |
| Type | IDs |
|---|---|
| Synonymous | APO-3, DDR3, DR3, GEF720, LARD, PLEKHG5, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR |
| Gene |
UniProtKB-ID:
TNR25_HUMAN
UniprotKB:
Q93038
UniParc:
UPI000002B5C2,
UPI000002B5C4,
UPI000002B5C9,
UPI000002B5CA,
UPI000003597B,
UPI000002B5C7,
UPI000002B5C8,
UPI000002B5C6,
UPI000002B5CC,
UPI000002B5C3,
UPI000002B5C5,
UPI000002B5CB
EMBL:
U83597,
U94506,
U83600,
AL158217,
U94502,
U94504,
U94507,
AY358309,
AB051851,
U94510,
U72763,
U83599,
U94501,
AF026070,
U75380,
U74611,
BC143886,
AB051850,
U94509,
U94512,
U75381,
Y09392,
U94503,
BC117189,
U94505,
AY254324,
U94508,
U83598,
AF026071,
U78029
Ensembl:
ENSG00000215788
KO:
hsa:8718
|
| Nucleutide sequences |
EMBL-CDS:
AAC51192.1,
AAC51316.1,
AAB39714.1,
AAB41435.1,
AAB41434.1,
AAB41433.1,
AAC51314.1,
AAO63495.1,
CAA70561.1,
AAB41432.1,
AAC51193.1,
BAB40662.1,
AAI17190.1,
CAA70560.1,
AAC51313.1,
AAC51309.1,
AAC51312.1,
AAC50819.1,
AAC39556.1,
BAB40663.1,
AAC51306.1,
AAC51310.1,
AAI43887.1,
AAC51308.1,
AAB82288.1,
CAA70559.1,
AAB40918.1,
AAC51315.1,
AAC51311.1,
AAQ88676.1,
AAC51307.1
Gene_ORFName:
UNQ455/PRO779
Ensembl_TRS:
ENST00000351748,
ENST00000510563,
ENST00000348333,
ENST00000485036,
ENST00000414040,
ENST00000356876,
ENST00000502730,
ENST00000351959,
ENST00000502588,
ENST00000377782
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000326762,
ENSP00000431554,
ENSP00000421976,
ENSP00000349341,
ENSP00000424071,
ENSP00000337713,
ENSP00000423121,
ENSP00000404274,
ENSP00000367013,
ENSP00000314451
RefSeq:
NP_001034753.1,
NP_683867.1,
NP_003781.1,
NP_683871.1,
NP_683868.1,
NP_683866.1
|
| Others |
UniRef100:
UniRef100_Q93038
UniRef90:
UniRef90_Q93038
UniRef50:
UniRef50_Q93038
UniGene:
Hs.462529
CCDS:
CCDS74.1,
CCDS71.1,
CCDS73.1,
CCDS75.1,
CCDS72.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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