| Type | Description |
|---|---|
| Definition | actinin alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:27:00 | High ACTN1 Is Associated with Poor Prognosis, and ACTN1 Silencing Suppresses and Metastasis in Oral Squamous Cell Carcinoma. | 32440097 |
| 2020-08-12 11:05:00 | The G764S and E769K mutations increase cytoskeletal association of actinin in cells, and all mutant proteins colocalize with F-actin in cultured HeLa cells. | 31365757 |
| 2020-05-09 13:35:00 | Report identifies 11 new variants in ACTN1 gene providing significant insight into the mechanisms of ACTN1-related thrombocytopenia (ACTN1-RT) and highlights the high frequency of congenital ACTN1 variants as a cause of inherited thrombocytopenia. The rod domain in ACTN1 may harbor variants resulting in actin disorganization in vitro and thrombocytopenia with normal platelet size in most cases. | 31237726 |
| 2020-05-09 11:15:00 | Hematopoietic cell-specific Lyn substrate, HCLS1, is a versatile actin-binding protein in leukocytes. (Review) | 30537294 |
| 2020-05-02 12:17:00 | The expression of fascin-1 and actinin-4 is connected with the degree of pancreatic intraepithelial neoplasia (PanIN) Advancement and depends on the type of the primary disease. Overexpression of these proteins may be linked to cytological and architectural abnormalities observed in advanced PanIN. | 31889512 |
| Type | IDs |
|---|---|
| Synonymous | BDPLT15 |
| Gene |
UniProtKB-ID:
ACTN1_HUMAN,
A0A024R694_HUMAN
UniprotKB:
P12814,
A0A024R694
UniParc:
UPI000188EF14,
UPI0000EE330A,
UPI0000D79B2C,
UPI0000043C25
EMBL:
BT007207,
BC015766,
AK295099,
BC003576,
CH471061,
X55187,
DQ496098,
GQ891539,
EU716325,
FJ410030,
X15804,
M95178,
AL117694
Ensembl:
ENSG00000072110
KO:
hsa:87
|
| Nucleutide sequences |
EMBL-CDS:
AAH15766.1,
CAA33803.1,
ACE62922.1,
EAW80975.1,
AAA51582.1,
ACJ24535.1,
BAG58135.1,
AAH03576.1,
AAP35871.1,
ABF50047.1,
CAA38970.1,
ADO22401.1,
EAW80971.1,
EAW80976.1
Gene_ORFName:
hCG_22243
Ensembl_TRS:
ENST00000438964,
ENST00000394419,
ENST00000193403,
ENST00000538545
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000193403,
ENSP00000414272,
ENSP00000439828,
ENSP00000377941
RefSeq:
XP_016877210.1,
XP_016877212.1,
XP_016877216.1,
XP_016877217.1,
NP_001123476.1,
XP_016877211.1,
XP_016877214.1,
XP_016877209.1,
XP_011535570.1,
XP_011535569.1,
XP_016877215.1,
XP_011535567.1,
NP_001093.1,
XP_011535568.1,
NP_001123477.1
|
| Others |
UniRef100:
UniRef100_P12814
UniRef90:
UniRef90_P12814
UniRef50:
UniRef50_P35609
UniGene:
Hs.509765
CCDS:
CCDS45130.1,
CCDS45129.1,
CCDS9792.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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