| Type | Description |
|---|---|
| Definition | sphingosine-1-phosphate receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:30:00 | NCF2, MYO1F, S1PR4, and FCN1 as potential noninvasive diagnostic biomarkers in patients with obstructive coronary artery: A weighted gene co-expression network analysis. | 31245869 |
| 2020-04-11 11:14:00 | T cell S1PR1 and S1PR4, and lymphatic endothelial cell (LEC) S1PR2, were required for migration across LECs and into lymphatic vessels and lymph nodes. S1PR1 and S1PR4 differentially regulated T cell motility and vascular cell adhesion molecule-1 (VCAM-1) binding. S1PR2 regulated LEC layer structure, permeability, and expression of the junction molecules VE-cadherin, occludin, and zonulin-1 through the ERK pathway. | 30877143 |
| 2018-03-03 11:19:00 | High S1PR4 expression is associated with anti-neutrophil cytoplasmic antibody-associated vasculitis. | 28206609 |
| 2017-09-09 14:25:00 | S1PR4 missense mutation is associated with variant blood cell traits. | 27399967 |
| 2017-06-10 10:30:00 | Shear stress did not induce rapid dephosphorylation of beta-arrestin-1 or rapid internalization of S1P3, indicating no GPCR activation. These findings suggest that Galphaq/11 participates in the sensing/transducing of shear stress independently of GPCR activation in ECs. | 28148497 |
| Type | IDs |
|---|---|
| Synonymous | EDG6, LPC1, S1P4, SLP4 |
| Gene |
UniProtKB-ID:
S1PR4_HUMAN
UniprotKB:
O95977
UniParc:
UPI0000050462
EMBL:
CH471139,
AY322537,
AJ000479,
BC014970
Ensembl:
ENSG00000125910
KO:
hsa:8698
|
| Nucleutide sequences |
EMBL-CDS:
CAA04118.1,
AAP84350.1,
AAH14970.1,
EAW69336.1,
EAW69337.1
Ensembl_TRS:
ENST00000246115
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000246115
RefSeq:
NP_003766.1
|
| Others |
UniRef100:
UniRef100_O95977
UniRef90:
UniRef90_O95977
UniRef50:
UniRef50_O95977
UniGene:
Hs.662006
CCDS:
CCDS12105.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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