| Type | Description |
|---|---|
| Definition | hyaluronidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:36:00 | HYAL1/2 suppress colorectal cancer cell metastasis by regulating MMPs/TIMPs balance and rearranging F-actin distribution, inhibiting invasion and migration of cancer cells. | 30972813 |
| 2019-10-05 11:55:00 | we discovered the existence of p47(phox) /Hyal2 complex. LSS induced the dissociation of p47(phox) /Hyal2 complex, which was inhibited by LKB1 overexpression and AICAR. Furthermore, knockdown of Hyal2 performed a positive feedback on LKB1 activity | 30078213 |
| 2018-06-30 12:28:00 | an important role for HYAL2 in CD44 alternative splicing. | 29162741 |
| 2018-05-19 11:09:00 | genetic variation in HYAL2 influences platelet aggregation | 28300864 |
| 2017-09-23 10:52:00 | Knocking down HYAL2 in HUVECs protected against HA degradation in the glycocalyx by inhibiting the expression and activity of HYAL2 and further blocked the dephosphorylation of eNOS-Ser-633 and the decrease in NO production in response to LSS. | 27798230 |
| Type | IDs |
|---|---|
| Synonymous | LUCA2 |
| Gene |
UniProtKB-ID:
HYAL2_HUMAN
UniprotKB:
Q12891
UniParc:
UPI000013C4E6
EMBL:
AJ000099,
AF070608,
AK127945,
AK092449,
U09577,
CH471055,
AC002455,
BC000692
Ensembl:
ENSG00000068001
KO:
hsa:8692
|
| Nucleutide sequences |
EMBL-CDS:
BAG52554.1,
AAC62823.1,
AAC28656.1,
AAB67045.1,
AAH00692.1,
EAW65092.1,
BAG54602.1,
CAA03924.1
Ensembl_TRS:
ENST00000442581,
ENST00000395139,
ENST00000447092,
ENST00000357750
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000406657,
ENSP00000350387,
ENSP00000401853,
ENSP00000378571
RefSeq:
XP_005265582.1,
XP_005265581.1,
NP_003764.3,
NP_149348.2
|
| Others |
UniRef100:
UniRef100_Q12891
UniRef90:
UniRef90_Q12891
UniRef50:
UniRef50_Q12891
UniGene:
Hs.76873
CCDS:
CCDS2818.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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