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8692 HYAL2

8692

HYAL2

hyaluronidase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition hyaluronidase 2

研究结论

Date Results Publications
2020-05-09 11:36:00 HYAL1/2 suppress colorectal cancer cell metastasis by regulating MMPs/TIMPs balance and rearranging F-actin distribution, inhibiting invasion and migration of cancer cells. 30972813
2019-10-05 11:55:00 we discovered the existence of p47(phox) /Hyal2 complex. LSS induced the dissociation of p47(phox) /Hyal2 complex, which was inhibited by LKB1 overexpression and AICAR. Furthermore, knockdown of Hyal2 performed a positive feedback on LKB1 activity 30078213
2018-06-30 12:28:00 an important role for HYAL2 in CD44 alternative splicing. 29162741
2018-05-19 11:09:00 genetic variation in HYAL2 influences platelet aggregation 28300864
2017-09-23 10:52:00 Knocking down HYAL2 in HUVECs protected against HA degradation in the glycocalyx by inhibiting the expression and activity of HYAL2 and further blocked the dephosphorylation of eNOS-Ser-633 and the decrease in NO production in response to LSS. 27798230

名称对应

Type IDs
Synonymous LUCA2
Gene
UniProtKB-ID: HYAL2_HUMAN
UniprotKB: Q12891
UniParc: UPI000013C4E6
EMBL: AJ000099, AF070608, AK127945, AK092449, U09577, CH471055, AC002455, BC000692
Ensembl: ENSG00000068001
KO: hsa:8692
Nucleutide sequences
EMBL-CDS: BAG52554.1, AAC62823.1, AAC28656.1, AAB67045.1, AAH00692.1, EAW65092.1, BAG54602.1, CAA03924.1
Ensembl_TRS: ENST00000442581, ENST00000395139, ENST00000447092, ENST00000357750
Protein sequencees
Ensembl_PRO: ENSP00000406657, ENSP00000350387, ENSP00000401853, ENSP00000378571
RefSeq: XP_005265582.1, XP_005265581.1, NP_003764.3, NP_149348.2
Others
UniRef100: UniRef100_Q12891
UniRef90: UniRef90_Q12891
UniRef50: UniRef50_Q12891
UniGene: Hs.76873
CCDS: CCDS2818.1

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