| Type | Description |
|---|---|
| Definition | macrophage receptor with collagenous structure |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 10:44:00 | MARCO is involved in hepatocellular carcinoma (HCC)progression and it can be defined as a novel probable biomarker as well as treatment target for HCC. | 31381879 |
| 2019-02-16 10:13:00 | Q452 and F282 are important for ligand association and phagocytosis of bacteria. Q452 and F282 are examples of positively selected mutations in MARCO, and both enhance the intrinsic function of the receptor. | 29165618 |
| 2018-07-28 11:40:00 | the absence of MARCO does not interfere with the efficiency of HSV-1 entry and that the inhibitory effect on viral adsorption by poly(I), a ligand of MARCO, is independent of MARCO. | 29769337 |
| 2018-06-30 12:13:00 | High surface expression of SR-A6 facilitates HAdV-C5 infection. | 29522575 |
| 2017-12-02 10:08:00 | These data suggest the SRCR domain of MARCO is the key domain in modulating ligand binding, enhancing downstream pro-inflammatory signaling and MARCO-mediated cellular adhesion. | 26888252 |
| Type | IDs |
|---|---|
| Synonymous | SCARA2, SR-A6 |
| Gene |
UniProtKB-ID:
MARCO_HUMAN,
Q4ZG40_HUMAN
UniprotKB:
Q9UEW3,
Q4ZG40
UniParc:
UPI0000000DF8,
UPI00017A8245
EMBL:
AF128174,
AF128179,
AF035819,
AF128177,
AF128185,
AF128172,
AK313139,
AK301407,
AF128180,
AF128175,
BC016004,
AF128173,
AC013457,
AF128186,
AF128182,
CH471103,
AF128178,
AF128176,
AF128184,
AF128183,
AF128181
Ensembl:
ENSG00000019169
KO:
hsa:8685
|
| Nucleutide sequences |
EMBL-CDS:
AAD41064.1,
AAH16004.1,
AAC08800.1,
BAG62941.1,
BAG35958.1,
AAX88875.1,
EAW95207.1
Gene_ORFName:
hCG_16205
Ensembl_TRS:
ENST00000327097
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000318916
RefSeq:
XP_016860660.1,
NP_006761.1,
XP_011510384.1,
XP_011510385.1
|
| Others |
UniRef100:
UniRef100_Q9UEW3
UniRef90:
UniRef90_Q9UEW3
UniRef50:
UniRef50_Q9UEW3
UniGene:
Hs.67726
CCDS:
CCDS2124.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员