| Type | Description |
|---|---|
| Definition | proliferation and apoptosis adaptor protein 15 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:24:00 | Non-Phosphorylatable PEA-15 Sensitises SKOV-3 Ovarian to Cisplatin. | 32102425 |
| 2020-04-18 10:50:00 | This study identified EA15, MIR22, and LINC00472 may serve as the potential diagnostic markers of diabetic nephropathy. | 30317603 |
| 2019-03-16 10:16:00 | Study results indicated that PEA15 expression was associated with clinicopathology and prognosis in gastric cancer and was regulated by AKT to participate in cisplatin resistance, indicating that it may be a potential target for overcoming cisplatin resistance in the treatment of gastric cancer. | 30569123 |
| 2019-01-26 11:47:00 | Study showed that PEA15 was highly expressed in colorectal cancer and liver metastatic cancer tissues and positively correlated with TNM staging, liver metastasis and poor prognosis. PEA15 may be a potential biomarker for liver metastasis of colorectal cancer therapy. Collectively, PEA15 promoted the development of liver metastasis of colorectal cancer through the ERK/MAPK signaling pathway. | 30365128 |
| 2018-07-07 10:54:00 | Data suggest that PED has a prominent role in HCC biology. It acts particularly on promoting cell migration and confers resistance to sorafenib treatment. | 29072691 |
| Type | IDs |
|---|---|
| Synonymous | HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15 |
| Gene |
UniProtKB-ID:
PEA15_HUMAN,
B1AKZ5_HUMAN,
Q96FS5_HUMAN,
B1AKZ4_HUMAN
UniprotKB:
Q15121,
B1AKZ5,
Q96FS5,
B1AKZ4
UniParc:
UPI000006EF84,
UPI000006E972,
UPI000013FA92,
UPI000046FCED
EMBL:
AL139011,
AL121987,
AF153273,
CH471121,
AK095879,
BC010469,
Y13736,
BC022554,
BC002426,
AK311762,
X86809,
AF153274,
BT007252
Ensembl:
ENSG00000162734
KO:
hsa:8682
|
| Nucleutide sequences |
EMBL-CDS:
AAD56775.1,
AAH02426.1,
AAH22554.1,
BAG53155.1,
CAA60499.1,
CAA74076.1,
EAW52735.1,
AAP35916.1,
AAH10469.1,
EAW52734.1,
BAG34705.1,
EAW52733.1
Gene_ORFName:
hCG_39732
Ensembl_TRS:
ENST00000360472,
ENST00000368076,
ENST00000368077
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000353660,
ENSP00000357055,
ENSP00000357056
RefSeq:
NP_001284507.1,
NP_001284505.1,
NP_001284506.1,
NP_003759.1,
XP_006711662.1
|
| Others |
UniRef100:
UniRef100_B1AKZ5,
UniRef100_Q96FS5,
UniRef100_Q15121
UniRef90:
UniRef90_A0A2R8MYY7,
UniRef90_Q96FS5,
UniRef90_Q15121
UniRef50:
UniRef50_Q61910,
UniRef50_Q62048,
UniRef50_P31415
UniGene:
Hs.517216
CCDS:
CCDS1199.1,
CCDS72954.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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