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8676 STX11

8676

STX11

syntaxin 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition syntaxin 11

研究结论

Date Results Publications
2020-01-25 10:28:00 STX11-deficient familial hemophagocytic lymphohistiocytosis type 4 is associated with self-resolving flares and a milder clinical course. 31207086
2019-01-12 10:08:00 Data suggest that acylation of SNAP23 (synaptosome associated protein 23) and STX11 (syntaxin-11) regulates exocytosis in platelets; maintaining acylation states of SNAP23 and STX11 is important for platelet function. 29352103
2018-08-11 10:11:00 Neonatal platelets exhibit low levels of the Stx11-Munc18b complex (essential component of the SNARE machinery) and of beta1-tubulin. These developmental deficiencies are associated with defects in platelet adhesion, spreading and secretion. 29044293
2016-02-20 10:27:00 The results suggest that STX11 plays an important role in the pathogenesis of Peripheral T-cell lymphomas and they may contribute to the future development of new drugs for the treatment of Peripheral T-cell lymphomas. 26176172
2015-06-20 11:03:00 a pivotal role for S-acylation in the function of syntaxin 11 in NK cells 24910990

名称对应

Type IDs
Synonymous FHL4, HLH4, HPLH4
Gene
UniProtKB-ID: STX11_HUMAN
UniprotKB: O75558
UniParc: UPI0000001C25
EMBL: CH471051, AF044309, AL135917, BC033519, AF038898, AF071504
Ensembl: ENSG00000135604
KO: hsa:8676
Nucleutide sequences
EMBL-CDS: AAC24004.1, AAH33519.1, EAW47850.1, AAD02107.1, EAW47849.1, AAC24031.1
Ensembl_TRS: ENST00000367568
Protein sequencees
Ensembl_PRO: ENSP00000356540
RefSeq: XP_011534515.1, XP_011534520.1, XP_011534516.1, NP_003755.2, XP_011534519.1, XP_016866889.1
Others
UniRef100: UniRef100_O75558
UniRef90: UniRef90_O75558
UniRef50: UniRef50_O75558
UniGene: Hs.118958
CCDS: CCDS5205.1

全选

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