| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 3 subunit H |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:21:00 | EIF3H Orchestrates Hippo Pathway-Mediated Oncogenesis via Catalytic Control of YAP Stability. | 32269044 |
| 2019-03-16 10:52:00 | METTL3-eIF3h interaction is required for enhanced translation, formation of densely packed polyribosomes and oncogenic transformation; findings uncover a mechanism of translation control that is based on mRNA looping and identify METTL3-eIF3h as a potential therapeutic target for patients with cancer | 30232453 |
| 2018-11-03 11:27:00 | EIF3H knockdown inhibited cell proliferation and colony formation in gastric cancer lines and led to cell cycle arrest at the G0/G1 phase, while inducing apoptosis via up- and downregulation of pro- and anti-apoptotic factors, respectively. These results indicate that EIF3H can serve as a novel therapeutic target for the clinical treatment of gastric cancer. | 30060823 |
| 2018-11-03 11:24:00 | EIF3H plays key roles in the apoptosis in colorectal cancer cells, which suggests EIF3H as a potential diagnostic biomarker in colorectal cancer | 30022709 |
| 2018-02-24 11:15:00 | eukaryotic translation initiation factor 3H has roles in proliferation, invasion and tumorigenicity in human hepatocellular carcinoma | 27340783 |
| Type | IDs |
|---|---|
| Synonymous | EIF3S3, eIF3-gamma, eIF3-p40 |
| Gene |
UniProtKB-ID:
EIF3H_HUMAN,
Q6IB98_HUMAN
UniprotKB:
O15372,
Q6IB98
UniParc:
UPI00000477E8
EMBL:
AF092576,
AF092569,
BT019594,
CH471060,
AF092573,
AF092574,
AF092571,
U54559,
AF092575,
BC000386,
AF092570,
AF092572,
CR456906
Ensembl:
ENSG00000147677
KO:
hsa:8667
|
| Nucleutide sequences |
EMBL-CDS:
AAC84044.1,
AAH00386.1,
AAD03465.1,
EAW91956.1,
CAG33187.1,
AAV38401.1
Gene_ORFName:
hCG_20900
Ensembl_TRS:
ENST00000521861
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000429931
RefSeq:
NP_003747.1
|
| Others |
UniRef100:
UniRef100_O15372
UniRef90:
UniRef90_O15372
UniRef50:
UniRef50_O15372
UniGene:
Hs.492599
CCDS:
CCDS6319.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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