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8665 EIF3F

8665

EIF3F

eukaryotic translation initiation factor 3 subunit F

protein-coding

Homo sapiens

基因描述

Type Description
Definition eukaryotic translation initiation factor 3 subunit F

研究结论

Date Results Publications
2020-06-20 12:49:00 Study discovered a role of interaction in the genetic control of cell migration and metastasis in human lung adenocarcinoma. EIF3F promotes lung cancer cell metastasis in vivo by regulating a cluster of 34 metastasis-promoting genes including Snail2. The interaction between EIF3F and controlled the EIF3F-mediated increase in Snail2 expression and cellular invasion. 31527668
2019-05-04 10:05:00 results underscore the importance of estrogen-ERalpha-mediated control of eIF3f expression for the proliferation and survival of ER-positive breast cancer cells. These findings may provide rationale for the development of new therapies to treat ER-positive breast cancer. 30573685
2017-02-18 12:18:00 The overexpression of eIF3f suppressed Akt and ERK signaling and subsequently depleted CLU expression. In addition, eIF3F stabilized p53, which increased the expression of p21 and Bax. 26988917
2016-01-30 11:45:00 eIF3f/alpha adrenergic receptor interaction 26497985
2015-02-07 10:13:00 Decreased expression of eukaryotic initiation factor 3f is associated with gastric cancer. 24678890

名称对应

Type IDs
Synonymous EIF3S5, MRT67, eIF3-p47
Gene
UniProtKB-ID: EIF3F_HUMAN
UniprotKB: O00303
UniParc: UPI000012D301
EMBL: BC000490, BT006894, CR456959, AK095574, U94855, AK289637, AK291354
Ensembl: ENSG00000175390
KO: hsa:8665
Nucleutide sequences
EMBL-CDS: AAP35540.1, CAG33240.1, AAH00490.1, BAF82326.1, BAC04577.1, BAF84043.1, AAD03467.1
Ensembl_TRS: ENST00000651655, ENST00000533626
Protein sequencees
Ensembl_PRO: ENSP00000431800, ENSP00000499218
RefSeq: NP_003745.1
Others
UniRef100: UniRef100_O00303
UniRef90: UniRef90_O00303
UniRef50: UniRef50_O00303
UniGene: Hs.516023
CCDS: CCDS7785.1

全选

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研究热度

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