| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 3 subunit D |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:57:00 | The current data highlight the importance of eIF3d in HIV infection by inhibiting CD8+ T cell function and promoting viral replication. | 31118081 |
| 2020-06-06 12:02:00 | EIF3D is a novel substrate of CUL3/KCTD10 ubiquitin ligase. The ubiquitin code of EIF3D is K27-polyubiquitination at the lysine 153 and 275 residues. | 31280863 |
| 2020-05-09 13:34:00 | Results demonstrated that the overexpression of eIF3D could independently predict poor prognosis for patients with lung adenocarcinoma (LUAD). In silico analysis demonstrated that the altered expression of eIF3D was at least regulated by both copy number alterations (CNAs) and the hypomethylation of cg14297023 site. | 31885740 |
| 2020-04-04 12:21:00 | Mechanistical study demonstrated that EIF3D interacted with GRP78 and enhanced protein stability through blocking the ubiquitin-mediated-proteasome degradation of GRP78. | 31669222 |
| 2018-07-14 12:01:00 | results indicate that eIF3D plays a key role in the proliferation of AML cells, and suggest that eIF3D silencing might be a potential therapeutic strategy for leukemia. | 28801778 |
| Type | IDs |
|---|---|
| Synonymous | EIF3S7, eIF3-p66, eIF3-zeta |
| Gene |
UniProtKB-ID:
EIF3D_HUMAN
UniprotKB:
O15371
UniParc:
UPI00017A7F80,
UPI00017A7E07,
UPI000012D306
EMBL:
CH471095,
AK300199,
AL022313,
BC093686,
BC000469,
BC080515,
U54558,
AK301284,
BC000328,
BC101477,
BC093100,
CR456489,
AK312939,
BT007381,
BC014912
Ensembl:
ENSG00000100353
KO:
hsa:8664
|
| Nucleutide sequences |
EMBL-CDS:
AAI01478.1,
AAH14912.1,
AAP36045.1,
AAH93686.1,
BAG61970.1,
AAH93100.1,
EAW60109.1,
BAG35781.1,
CAG30375.1,
BAG62843.1,
AAH80515.1,
AAH00328.1,
AAH00469.1,
AAD03466.1
Ensembl_TRS:
ENST00000405442,
ENST00000216190
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216190,
ENSP00000385812
RefSeq:
NP_003744.1
|
| Others |
UniRef100:
UniRef100_O15371
UniRef90:
UniRef90_O15371
UniRef50:
UniRef50_O15371
UniGene:
Hs.55682
CCDS:
CCDS13930.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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