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8661 EIF3A

8661

EIF3A

eukaryotic translation initiation factor 3 subunit A

protein-coding

Homo sapiens

基因描述

Type Description
Definition eukaryotic translation initiation factor 3 subunit A

研究结论

Date Results Publications
2020-08-12 14:38:00 Results found EIF3A highly expressed lung cancer and has a significant effect on the survival rate of the patients. 31197975
2020-02-15 13:11:00 Here, the authors show that human eukaryotic translation initiation factor 3 (eIF3) acts as a distinct repressor of FTL mRNA translation, and eIF3-mediated FTL repression is disrupted by a subset of single nucleotide polymorphisms in FTL that cause hyperferritinemia. 31414986
2019-03-09 12:37:00 siRNA-mediated silencing of eIF3a reduced the polysome-to-monosome ratio in F508del-expressing cells, which, in turn, decreased the translation of CFTR variants, leading to increased CFTR stability, trafficking, and function at the cell surface. 30006345
2018-10-27 11:18:00 miRNA-488 participates in eIF3a mediated cisplatin resistance in non-small-cell lung cance cells. 28074905
2018-08-18 10:03:00 Knockdown of elF3a inhibits TGFB1-induced extracellular matrix protein expression in keloid fibroblasts. 29286129

名称对应

Type IDs
Synonymous EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185
Gene
UniProtKB-ID: EIF3A_HUMAN
UniprotKB: Q14152
UniParc: UPI000012D311, UPI0002064F6B
EMBL: CH471066, D50929, U78311, AL355598, U58047, U58046, AK302575
Ensembl: ENSG00000107581
KO: hsa:8661
Nucleutide sequences
EMBL-CDS: AAB41586.1, AAB41584.1, AAB80695.1, EAW49408.1, BAG63833.1, BAA09488.2
Ensembl_TRS: ENST00000541549, ENST00000369144
Protein sequencees
Ensembl_PRO: ENSP00000358140, ENSP00000438178
RefSeq: NP_003741.1
Others
UniRef100: UniRef100_Q14152
UniRef90: UniRef90_Q14152
UniRef50: UniRef50_Q14152
UniGene: Hs.523299
CCDS: CCDS7608.1

全选

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