| Type | Description |
|---|---|
| Definition | serpin family A member 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:50:00 | Pyrexia and acidosis act independently of neutrophil elastase reactive center loop cleavage to effect cortisol release from corticosteroid-binding globulin. | 33085168 |
| 2020-06-06 11:05:00 | Here, we show that these issues can be addressed concurrently, using the serpin human a1-antichymotrypsin (ACT) as a model. We have introduced up to 15 amino acid substitutions into ACT, converting it into a surrogate corticosteroid-binding globulin (CBG), thereby creating a new binding globulin (NewBG). | 31103428 |
| 2020-03-21 12:09:00 | Low circulating haCBG concentrations are associated with mortality in septic shock | 30160799 |
| 2019-10-26 10:34:00 | Mass spectrometry confirmed the absence of neutrophil elastase (NE)-cleaved corticosteroid-binding globulin (CBG) in plasma in which ELISA values were highly discordant. | 30452386 |
| 2019-09-14 11:41:00 | N-glycans at other sites also appear to protect CBG from neutrophil elastase or chymotrypsin. | 29273683 |
| Type | IDs |
|---|---|
| Synonymous | CBG |
| Gene |
UniProtKB-ID:
CBG_HUMAN,
A0A2Z4LCH4_HUMAN
UniprotKB:
P08185,
A0A2Z4LCH4
UniParc:
UPI00001BB2AE,
UPI0000127182
EMBL:
CH471061,
J02943,
MG652288,
BC058021,
AK290821,
BC056259
Ensembl:
ENSG00000277405,
ENSG00000170099
KO:
hsa:866
|
| Nucleutide sequences |
EMBL-CDS:
AAH56259.1,
AAH58021.1,
BAF83510.1,
EAW81568.1,
AAB59523.1,
AWX34100.1
Ensembl_TRS:
ENST00000341584,
ENST00000621384
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342850,
ENSP00000484501
RefSeq:
NP_001747.3
|
| Others |
UniRef100:
UniRef100_P08185,
UniRef100_A0A2Z4LCH4
UniRef90:
UniRef90_P08185
UniRef50:
UniRef50_P08185
UniGene:
Hs.532635
CCDS:
CCDS9924.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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