| Type | Description |
|---|---|
| Definition | dynein light chain LC8-type 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:51:00 | DYNLL1 is hypomethylated and upregulated in a tumor stage- and grade-dependent manner and associated with increased mortality in hepatocellular carcinoma. | 33171156 |
| 2020-03-21 11:44:00 | The multiple associations of the regulatory proteins of the microtubule network could ensure fine tuning in the regulation of the intracellular trafficking process either by the complexation of DYNLL/LC8 with new partners or indirectly by the modulation of the acetylation level of the microtubule network. | 31505170 |
| 2020-02-29 11:58:00 | The data establish LC8 as an important mediator of a subset of 53BP1-dependent DNA double-strand breaks responses. | 30982887 |
| 2019-12-21 10:28:00 | identification of recognition motifs for binding partners for the hub protein LC8. | 31266884 |
| 2019-05-18 12:09:00 | DYNLL1 binds directly to MRE11 to limit its end-resection activity; it is inferred that DYNLL1 is an important anti-resection factor that influences genomic stability and responses to DNA-damaging chemotherapy | 30464262 |
| Type | IDs |
|---|---|
| Synonymous | DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, PIN, hdlc1 |
| Gene |
UniProtKB-ID:
DYL1_HUMAN,
Q6FGH9_HUMAN
UniprotKB:
P63167,
Q6FGH9
UniParc:
UPI0000000991
EMBL:
BC104244,
CR407672,
CH471054,
CR542128,
AK311790,
U32944,
BC104245,
BC100289
Ensembl:
ENSG00000088986
KO:
hsa:8655
|
| Nucleutide sequences |
EMBL-CDS:
CAG28600.1,
AAB04149.1,
EAW98195.1,
EAW98197.1,
EAW98196.1,
BAG34733.1,
AAI04245.1,
AAI00290.1,
CAG46925.1,
AAI04246.1
Gene_ORFName:
hCG_27767
Ensembl_TRS:
ENST00000548342,
ENST00000242577,
ENST00000392509,
ENST00000392508,
ENST00000549989
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000447907,
ENSP00000376296,
ENSP00000376297,
ENSP00000242577,
ENSP00000446614
RefSeq:
NP_001032583.1,
NP_003737.1,
NP_001032584.1
|
| Others |
UniRef100:
UniRef100_P63167
UniRef90:
UniRef90_P63167
UniRef50:
UniRef50_P63167
UniGene:
Hs.5120
CCDS:
CCDS9200.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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