| Type | Description |
|---|---|
| Definition | nuclear receptor coactivator 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:26:00 | Steroid receptor coactivator-1 enhances the stemness of glioblastoma by activating long noncoding RNA XIST/miR-152/KLF4 pathway. | 33090636 |
| 2020-08-01 12:53:00 | SRF-FOXO1 and SRF-NCOA1 gene fusion occurs in a subset of well differentiated rhabdomyosarcoma of the neck muscles. | 32187044 |
| 2020-02-01 12:25:00 | Src-1 and Twist1 were aberrantly upregulated in nasopharyngeal carcinoma (NPC) tissues, and associated with advanced tumor stage, distant metastasis and unfavorable prognosis. Knockdown of Src-1 or Twist1 in NPC cell line CNE-1 suppressed colony formation, anchorage-independent growth, cell migration, invasion and tumor xenografts growth. | 30973923 |
| 2019-06-29 12:16:00 | FXR and RXR bind to the transcriptional coregulator steroid receptor coactivator 1 with higher affinity when they are part of the heterodimer complex than when they are in their respective monomeric states. | 30275017 |
| 2019-05-11 12:20:00 | fifteen rare heterozygous variants in SRC-1 found in severely obese individuals impair leptin-mediated Pomc reporter activity in cells, whilst four variants found in non-obese controls do not | 30979869 |
| Type | IDs |
|---|---|
| Synonymous | F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74 |
| Gene |
UniProtKB-ID:
NCOA1_HUMAN
UniprotKB:
Q15788
UniParc:
UPI000006E1F7,
UPI000006E990,
UPI0000160FFC
EMBL:
EF660499,
BC111533,
AC013459,
U40396,
AJ000882,
AC093798,
AJ000881,
U90661,
U19179,
U59302,
CH471053,
BC111534,
AY633656
Ensembl:
ENSG00000084676
KO:
hsa:8648
|
| Nucleutide sequences |
EMBL-CDS:
AAI11535.1,
AAC50305.1,
EAX00746.1,
AAI11534.1,
AAX93184.1,
CAA04371.1,
AAT47737.1,
CAA04372.1,
ABS29266.1,
AAC50631.1,
AAA64187.1,
AAB50242.1
Ensembl_TRS:
ENST00000395856,
ENST00000406961,
ENST00000288599,
ENST00000405141,
ENST00000348332
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385216,
ENSP00000320940,
ENSP00000379197,
ENSP00000385097,
ENSP00000288599
RefSeq:
XP_005264683.1,
NP_671756.1,
NP_001349879.1,
NP_671766.1,
NP_001349884.1,
NP_001349881.1,
NP_003734.3,
XP_005264682.1,
NP_001349883.1
|
| Others |
UniRef100:
UniRef100_Q15788
UniRef90:
UniRef90_Q15788
UniRef50:
UniRef50_Q15788
UniGene:
Hs.596314
CCDS:
CCDS42660.1,
CCDS1712.1,
CCDS1713.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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