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8647 ABCB11

8647

ABCB11

ATP binding cassette subfamily B member 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATP binding cassette subfamily B member 11

研究结论

Date Results Publications
2021-04-17 13:15:00 The Bile Salt Export Pump: Molecular Structure, Study Models and Small-Molecule Drugs for the Treatment of Inherited BSEP Deficiencies. 33466755
2021-01-02 12:53:00 Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion. 33031417
2020-12-12 13:29:00 Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. 33020312
2020-12-05 12:56:00 Phenotype-Genotype Correlation of North Indian Progressive Familial Intrahepatic Cholestasis type2 Children Shows p.Val444Ala and p.Asn591Ser Variants and Retained BSEP Expression. 31335238
2020-07-11 11:29:00 Our results demonstrated increased expression of ABCB11 and ABCB4 on protein as well as RNA level in primary sclerosing cholangitis, and the expression pattern correlated with disease progression. 31886153

名称对应

Type IDs
Synonymous ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP
Gene
UniProtKB-ID: ABCBB_HUMAN
UniprotKB: O95342
UniParc: UPI0000163BFA
EMBL: AC093723, AC008177, AC069137, AF091582, AF136523
Ensembl: ENSG00000073734
KO: hsa:8647
Nucleutide sequences
EMBL-CDS: AAY24305.1, AAC77455.1, AAD28285.1
Ensembl_TRS: ENST00000650372
Protein sequencees
Ensembl_PRO: ENSP00000497931
RefSeq: NP_003733.2, XP_011510383.1, XP_011510382.1, XP_011510379.1, XP_011510380.1, XP_006712880.1, XP_016860654.1, XP_016860655.1, XP_016860656.1
Others
UniRef100: UniRef100_O95342
UniRef90: UniRef90_O95342
UniRef50: UniRef50_O95342
UniGene: Hs.658439
CCDS: CCDS46444.1

全选

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