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8644 AKR1C3

8644

AKR1C3

aldo-keto reductase family 1 member C3

protein-coding

Homo sapiens

基因描述

Type Description
Definition aldo-keto reductase family 1 member C3

研究结论

Date Results Publications
2021-01-16 16:01:00 AKR1C3 mediates pan-AR antagonist resistance in castration-resistant prostate cancer. 33258507
2020-12-12 13:30:00 Significance of aldo-keto reductase 1C3 and ATP-binding cassette transporter B1 in gain of irinotecan resistance in colon cancer cells. 33096057
2020-09-05 13:53:00 Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis. 31780644
2020-07-11 11:27:00 Results suggest that aryl hydrocarbon receptor (AhR) and aldo-keto reductase (AKR) 1C3 (AKR1C3) expression were positively correlated in human breast cancer. 31253396
2020-06-13 10:57:00 the AKR1C3/AR-V7 complex collaboratively confers resistance to AR-targeted therapies in advanced prostate cancer. 31308078

名称对应

Type IDs
Synonymous DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS
Gene
UniProtKB-ID: AK1C3_HUMAN, A0A0A0MSS8_HUMAN, B4DKT3_HUMAN
UniprotKB: P42330, A0A0A0MSS8, B4DKT3
UniParc: UPI0000EE4135, UPI00023B37D2, UPI00017A74FE, UPI0000140951
EMBL: KF455197, BT007286, L43836, L43839, L43834, AB032157, AF149416, L43833, AL391427, CH471072, L43832, AB018580, BC019230, L43831, L43838, S68288, AB028065, AK296701, BC001479, L43835, L43837, AK296829, D17793, AK290365
Ensembl: ENSG00000196139
KO: hsa:8644
Nucleutide sequences
EMBL-CDS: BAA88488.1, AAH19230.1, BAG59399.1, BAA04619.2, BAA88489.1, AAH01479.1, BAF83054.1, BAA92892.1, AAD14011.1, AAP35950.1, AAF07272.2, EAW86454.1, AAB41916.1, BAG59295.1
Ensembl_TRS: ENST00000380554, ENST00000439082
Protein sequencees
Ensembl_PRO: ENSP00000369927, ENSP00000401327
RefSeq: NP_001240837.1, NP_001240838.1, NP_003730.4
Others
UniRef100: UniRef100_B4DKT3, UniRef100_P42330, UniRef100_A0A0A0MSS8
UniRef90: UniRef90_P42330, UniRef90_B4DKT3, UniRef90_Q5R7C9
UniRef50: UniRef50_P52895-2, UniRef50_P42330, UniRef50_Q5R7C9
UniGene: Hs.78183
CCDS: CCDS7063.1

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